Parkinson's disease is a progressive neurodegenerative disease characterized by tremor
and bradykinesia and is a common neurologic ailment. Male sex and advancing age are …

Abstract Interpretation of clinical trials comparing different drug regimens for Parkinson's
disease (PD) is complicated by the different dose intensities used: higher doses of levodopa …

High-frequency deep brain stimulation (DBS) of the subthalamic nucleus (STN-HFS) is the
preferred surgical treatment for advanced Parkinson's disease. In the 15 years since its …

Although deep brain stimulation (DBS) of the globus pallidus internus (GPi) and the
subthalamic nucleus (STN) has become an established treatment for Parkinson's disease …

During the last 15 years deep brain stimulation (DBS) has been established as a highly-
effective therapy for advanced Parkinson's disease (PD). Patient selection, stereotactic …

Background Deep brain stimulation (DBS) of the subthalamic nucleus is an established
therapeutic option for managing motor symptoms of Parkinson's disease. We conducted a …

The demonstration that dopamine loss is the key pathological feature of Parkinson's disease
(PD), and the subsequent introduction of levodopa have revolutionalized the field of PD …

Abstract Introduction Deep Brain Stimulation (DBS) is an effective treatment extended
broadly to many neurological and psychiatric disorders. Nevertheless, complications may …

Objective To find predictors of cognitive decline and quality of life 1 year after bilateral
subthalamic nucleus deep brain stimulation (STN DBS) in Parkinson's disease (PD) …

Involvement of the olfactory bulb by Lewy-type α-synucleinopathy (LTS) is known to occur at
an early stage of Parkinson's disease (PD) and Lewy body disorders and is therefore of …