Neurotransmitters and neuromodulators have a wide range of key roles throughout the
nervous system. However, their dynamics in both health and disease have been challenging …

Spatial metabolomics is an emerging field of omics research that has enabled localizing
metabolites, lipids, and drugs in tissue sections, a feat considered impossible just two …

Timely screening of neuromyelitis optica spectrum disorder (NMOSD) and differential
diagnosis from myelin oligodendrocyte glycoprotein associated disorder (MOGAD) are the …

Compared with conventional optical microscopy techniques, mass spectrometry imaging
(MSI) or imaging mass spectrometry (IMS) is a powerful, label-free analytical technique …

We present a spatial omics approach that combines histology, mass spectrometry imaging
and spatial transcriptomics to facilitate precise measurements of mRNA transcripts and low …

Identification of novel non‐invasive biomarkers is critical for the early diagnosis of lung
adenocarcinoma (LUAD), especially for the accurate classification of pulmonary nodule …

Prosaposin (PSAP) modulates glycosphingolipid metabolism and variants have been linked
to Parkinson's disease (PD). Here, we find altered PSAP levels in the plasma, CSF and post …

Mass spectrometry imaging (MSI) is an emerging technology in cancer metabolomics.
Desorption electrospray ionization (DESI) and matrix-assisted laser desorption ionization …

Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) is a fast-
growing technique for visualization of the spatial distribution of the small molecular and …

Imaging mass spectrometry has become a mature molecular mapping technology that is
used for molecular discovery in many medical and biological systems. While powerful by …