Tyrosinase is a key enzyme target to design new chemical ligands against melanogenesis.
In the current review, different chemical derivatives are explored which have been used as …

The evolutionarily ancient methoxyindoleamine, melatonin, has long perplexed investigators
by its versatility of functions and mechanisms of action, which include the regulation of …

The skin is the largest organ of the body and consists of an epidermis, dermis and
subcutaneous adipose tissue. The skin surface area is often stated to be about 1.8 to 2 m2 …

Skin pigmentation ensures efficient photoprotection and relies on the pigment melanin,
which is produced by epidermal melanocytes and transferred to surrounding keratinocytes …

Aldehydes fixation was accidentally discovered in the early 20th century and soon became a
widely adopted practice in the histological field, due to an excellent staining enhancement in …

Simple Summary Melanoma is produced by the malignant transformation of the pigmented
cells in the skin. It is the deadliest form of skin cancer and a global medical burden. Recent …

Cutaneous melanoma can be a most challenging neoplasm of high lethality, in part due to
its extreme heterogeneity and characteristic aggressive and invasive nature. Indeed, its …

Background The flavonoids and polysaccharides in Portulaca oleracea L.(PO) have
significant antibacterial and antioxidant effects, which can inhibit common bacteria and …

Background Human Immunodeficiency Virus (HIV) infects patients via CD4+ cells which are
later be destroyed subsequently causing the deteriotation of immune system. HIV generally …

Background The pursuit for safe and efficacious skin-whitening agents has prompted a
dedicated exploration of plant-derived compounds. Notably, Tagetes erecta L. flowers have …