Snakebite envenoming is a neglected tropical disease that kills> 100,000 people and
maims> 400,000 people every year. Impoverished populations living in the rural tropics are …

Published research on fucoidans increased three fold between 2000 and 2010. These algal
derived marine carbohydrate polymers present numerous valuable bioactivities. This review …

The availability of effective, reliably accessible, and affordable treatments for snakebite
envenoming is a critical and long unmet medical need. Recently, small, synthetic toxin …

Muscle necrosis is a potential clinical complication of snakebite envenomings, which in
severe cases can lead to functional or physical sequelae such as disability or amputation …

Envenomations by Bothrops asper are often associated with complex and severe local
pathological manifestations, including edema, blistering, dermonecrosis, myonecrosis and …

Snakebite envenoming is an important public health issue responsible for mortality and
severe morbidity. Where mortality is mainly caused by venom toxins that induce …

Inflammation is a major characteristic of envenomation by snakes from viperine and
crotaline species. Bothrops asper snake venom elicits, among other alterations, a …

Envenomation by viperid snakes is characterized by systemic thrombotic syndrome and
prominent local inflammation. To date, the mechanisms underlying inflammation and blood …

Polymorphonuclear neutrophils are the most abundant leukocytes in the blood and
constitute key components of the innate immunity. Upon infection or tissue damage …

Venomous snake bite adversely affects millions of people yearly, but few animal models
allow for the determination of toxicodynamic timelines with hemotoxic venoms to …