Melatonin in macrophage biology: Current understanding and future perspectives

Y Xia, S Chen, S Zeng, Y Zhao, C Zhu… - Journal of pineal …, 2019 - Wiley Online Library
Melatonin is a ubiquitous hormone found in various organisms and highly affects the
function of immune cells. In this review, we summarize the current understanding of the …

Melatonin: another avenue for treating osteoporosis?

T Li, S Jiang, C Lu, W Yang, Z Yang… - Journal of pineal …, 2019 - Wiley Online Library
Melatonin is a signal molecule that modulates the biological circadian rhythms of
vertebrates. Melatonin deficiency is thought to be associated with several disorders …

[HTML][HTML] Melatonin enhances osteogenic differentiation of dental pulp mesenchymal stem cells by regulating MAPK pathways and promotes the efficiency of bone …

YH Chan, KN Ho, YC Lee, MJ Chou, WZ Lew… - Stem Cell Research & …, 2022 - Springer
Background Mesenchymal stem cell (MSC)-based tissue engineering plays a major role in
regenerative medicine. However, the efficiency of MSC transplantation and survival of …

Recent developed strategies for enhancing Chondrogenic differentiation of MSC: impact on MSC‐based therapy for cartilage regeneration

K Zha, Z Sun, Y Yang, M Chen, C Gao… - Stem Cells …, 2021 - Wiley Online Library
Articular cartilage is susceptible to damage, but its self‐repair is hindered by its avascular
nature. Traditional treatment methods are not able to achieve satisfactory repair effects, and …

[HTML][HTML] Bacteriostatic potential of melatonin: therapeutic standing and mechanistic insights

F He, X Wu, Q Zhang, Y Li, Y Ye, P Li, S Chen… - Frontiers in …, 2021 - frontiersin.org
Diseases caused by pathogenic bacteria in animals (eg, bacterial pneumonia, meningitis
and sepsis) and plants (eg, bacterial wilt, angular spot and canker) lead to high prevalence …

Plant-derived melatonin from food: a gift of nature

G Cheng, T Ma, Z Deng, G Gutiérrez-Gamboa, Q Ge… - Food & Function, 2021 - pubs.rsc.org
In recent years, people have become increasingly interested in bioactive ingredients from
plants, especially antioxidant molecules such as melatonin, which are beneficial to human …

[HTML][HTML] The lncRNA H19/miR-541-3p/Wnt/β-catenin axis plays a vital role in melatonin-mediated osteogenic differentiation of bone marrow mesenchymal stem cells

H Han, T Tian, G Huang, D Li, S Yang - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
Implant dentures become the first choice for denture restoration in patients with tooth loss.
However, oral implants often fail in osteoporosis (OP) patients. Melatonin (MT) induces …

Melatonin interrupts osteoclast functioning and suppresses tumor-secreted RANKL expression: implications for bone metastases

PI Liu, AC Chang, JL Lai, TH Lin, CH Tsai, PC Chen… - Oncogene, 2021 - nature.com
Cancer-related bone erosion occurs frequently in bone metastasis and is associated with
severe complications such as chronic bone pain, fractures, and lower survival rates. In …

Melatonin and bone-related diseases: an updated mechanistic overview of current evidence and future prospects

A Bagherifard, A Hosseinzadeh, F Koosha… - Osteoporosis …, 2023 - Springer
Purpose Bone diseases account for an enormous cost burden on health systems. Bone
disorders are considered as age-dependent diseases. The aging of world population has …

Melatonin enhances osteoblastogenesis of senescent bone marrow stromal cells through NSD2‐mediated chromatin remodelling

Y Xie, N Han, F Li, L Wang, G Liu, M Hu… - Clinical and …, 2022 - Wiley Online Library
Background Aging‐associated osteoporosis is frequently seen in the elderly in clinic, but
efficient managements are limited because of unclear nosogenesis. The current study aims …