[HTML][HTML] Enzymes revolutionize the bioproduction of value-added compounds: From enzyme discovery to special applications

B Wiltschi, T Cernava, A Dennig, MG Casas… - Biotechnology …, 2020 - Elsevier
Competitive sustainable production in industry demands new and better biocatalysts,
optimized bioprocesses and cost-effective product recovery. Our review sheds light on the …

Phytostilbenes as agrochemicals: Biosynthesis, bioactivity, metabolic engineering and biotechnology

P Jeandet, A Vannozzi, E Sobarzo-Sánchez… - Natural product …, 2021 - pubs.rsc.org
Covering: 1976 to 2020. Although constituting a limited chemical family, phytostilbenes
represent an emblematic group of molecules among natural compounds. Ever since their …

Development of a Bacterial Biosensor for Rapid Screening of Yeast p-Coumaric Acid Production

S Siedler, NK Khatri, A Zsohar, I Kjærbølling… - ACS synthetic …, 2017 - ACS Publications
Transcription factor-based biosensors are used to identify producer strains, a critical
bottleneck in cell factory engineering. Here, we address two challenges with this …

Metabolic engineering of Escherichia coli for microbial synthesis of monolignols

Z Chen, X Sun, Y Li, Y Yan, Q Yuan - Metabolic engineering, 2017 - Elsevier
Monolignols are important plant metabolites involved in lignin biosynthesis. Their derivatives
exhibit various physiological and pharmaceutical functions. Here, efficient enzymes were …

Production of plant-derived polyphenols in microorganisms: current state and perspectives

L Milke, J Aschenbrenner, J Marienhagen… - Applied Microbiology …, 2018 - Springer
Plants synthesize several thousand different polyphenols of which many have the potential
to aid in preventing or treating cancer, cardiovascular, and neurodegenerative diseases …

Functional expression of plant-derived O-methyltransferase, flavanone 3-hydroxylase, and flavonol synthase in Corynebacterium glutamicum for production of …

N Kallscheuer, M Vogt, M Bott, J Marienhagen - Journal of biotechnology, 2017 - Elsevier
Plant polyphenols receive significant attention due to their anti-oxidative and health-
promoting properties, and several microorganisms are currently engineered towards …

Engineering stilbene metabolic pathways in microbial cells

P Jeandet, E Sobarzo-Sánchez, C Clément… - Biotechnology …, 2018 - Elsevier
Numerous in vitro and in vivo studies on biological activities of phytostilbenes have brought
to the fore the remarkable properties of these compounds and their derivatives, making them …

Reversal of β-oxidative pathways for the microbial production of chemicals and polymer building blocks

N Kallscheuer, T Polen, M Bott, J Marienhagen - Metabolic engineering, 2017 - Elsevier
Abstract β-Oxidation is the ubiquitous metabolic strategy to break down fatty acids. In the
course of this four-step process, two carbon atoms are liberated per cycle from the fatty acid …

Exploiting members of the BAHD acyltransferase family to synthesize multiple hydroxycinnamate and benzoate conjugates in yeast

A Eudes, M Mouille, DS Robinson, VT Benites… - Microbial cell …, 2016 - Springer
Background BAHD acyltransferases, named after the first four biochemically characterized
enzymes of the group, are plant-specific enzymes that catalyze the transfer of coenzyme A …

Whole-Cell Bioconversion Systems for Efficient Synthesis of Monolignols from L-Tyrosine in Escherichia coli

M Zhao, B Zhang, X Wu, Y Xiao - Journal of Agricultural and Food …, 2024 - ACS Publications
Monolignols and their derivatives exhibit various pharmaceutical and physiological
characteristics, such as antioxidant and anti-inflammatory properties. However, they remain …