Since the discovery of glucocorticoids in the 1940s and the recognition of their anti-
inflammatory effects, they have been amongst the most widely used and effective treatments …

Preterm birth occurs in 11% of live births globally and accounts for 35% of all newborn
deaths. Preterm newborns have immature immune systems, with reduced innate and …

Context: Glucocorticoids are effective for severe Graves' orbitopathy (GO), which causes
substantial morbidity. The question at issue is how best to use them. Objective: The objective …

Glucocorticoids (GCs) are a class of steroid hormones which regulate a variety of essential
biological functions. The profound anti-inflammatory and immunosuppressive activity of …

The muscle specific ubiquitin E3 ligase MuRF1 has been implicated as a key regulator of
muscle atrophy under a variety of conditions, such as during synthetic glucocorticoid …

Objective: Electrical vagus nerve stimulation inhibits proinflammatory cytokine production
and prevents shock during lethal systemic inflammation through an [alpha] 7 nicotinic …

Over the past 40 years, it has been recognised that the maternal hypothalamic‐pituitary‐
adrenal (HPA) axis undergoes adaptations through pregnancy and lactation that might …

For many decades, glucocorticoids have been widely used as the gold standard treatment
for inflammatory conditions. Unfortunately, their clinical use is limited by severe adverse …

A cure for type 1 diabetes (T1D) would help millions of people worldwide but remains
elusive to date. Tolerogenic vaccines and β-cell replacement therapy are complementary …

Transplant-associated inflammatory responses generate an unfavorable microenvironment
for tissue engraftment, particularly for cells susceptible to inflammatory stress, such as …