Heparin: An old drug for new clinical applications
P Wang, L Chi, Z Zhang, H Zhao, F Zhang… - Carbohydrate …, 2022 - Elsevier
Heparin, an old but first-line anticoagulant, has been used over a century. It is a
heterogeneous, linear, highly sulfated, anionic glycosaminoglycan with a broad distribution …
heterogeneous, linear, highly sulfated, anionic glycosaminoglycan with a broad distribution …
Polysaccharide-based hydrogels for medical devices, implants and tissue engineering: A review
Hydrogels are highly biocompatible biomaterials composed of crosslinked three-
dimensional networks of hydrophilic polymers. Owing to their natural origin, polysaccharide …
dimensional networks of hydrophilic polymers. Owing to their natural origin, polysaccharide …
Construction of a novel MPT-driven necrosis-related lncRNAs signature for prognosis prediction in laryngeal squamous cell carcinoma
J Liu, M Zhang, Q Sun, X Qin, T Gao, Y Xu… - … Science and Pollution …, 2023 - Springer
Mitochondrial permeability transition (MPT)-driven necrosis, a type of programmed cell
death, has recently gained much attention in a variety of tumor types. Few studies have been …
death, has recently gained much attention in a variety of tumor types. Few studies have been …
[HTML][HTML] The role and therapeutic value of syndecan-1 in cancer metastasis and drug resistance
S Guo, XY Wu, T Lei, R Zhong, YR Wang… - Frontiers in Cell and …, 2022 - frontiersin.org
Metastasis and relapse are major causes of cancer-related fatalities. The elucidation of
relevant pathomechanisms and adoption of appropriate countermeasures are thus crucial …
relevant pathomechanisms and adoption of appropriate countermeasures are thus crucial …
The heparan sulfate mimetic Muparfostat aggravates steatohepatitis in obese mice due to its binding affinity to lipoprotein lipase
J Zhang, K Li, HR Sun, SK Sun, YT Zhu… - British Journal of …, 2023 - Wiley Online Library
Background and Purpose Heparanase is the only confirmed endoglycosidase that cleaves
heparan sulfate (HS), a ubiquitous glycosaminoglycan with various essential roles in …
heparan sulfate (HS), a ubiquitous glycosaminoglycan with various essential roles in …
[HTML][HTML] Heparanase promotes malignant phenotypes of human oral squamous carcinoma cells by regulating the epithelial-mesenchymal transition-related molecules …
C Wang, Y Huang, B Jia, Y Huang, J Chen - Archives of Oral Biology, 2023 - Elsevier
Objectives The aim of the present study was to explore the functional role of heparanase
(HPSE) and investigate the effect of HPSE on epithelial-mesenchymal transition (EMT) and …
(HPSE) and investigate the effect of HPSE on epithelial-mesenchymal transition (EMT) and …
[HTML][HTML] Research progress on microRNA-1258 in the development of human cancer
M Qian, Y Xia, G Zhang, H Yu, Y Cui - Frontiers in Oncology, 2022 - frontiersin.org
microRNAs (miRNAs) are small endogenous RNAs composed of 20-22 nucleotides that do
not encode proteins, which regulate the expression of downstream genes by targeting the …
not encode proteins, which regulate the expression of downstream genes by targeting the …