Research efforts during the past decades have provided intriguing evidence suggesting that
stressful experiences during pregnancy exert long-term consequences on the future mental …

Psychiatric disorders are complex multifactorial illnesses involving chronic alterations in
neural circuit structure and function as well as likely abnormalities in glial cells. While …

The current review focuses on studies in rodents published since 2008 and explores
possible reasons for any differences they report in the effects of gestational stress on various …

Dynamic DNA modifications, such as methylation/demethylation on cytosine, are major
epigenetic mechanisms to modulate gene expression in both eukaryotes and prokaryotes. In …

During the last decades, schizophrenia has been regarded as a developmental disorder.
The neurodevelopmental hypothesis proposes schizophrenia to be related to genetic and …

Adverse experiences during gestation such as maternal stress and infection are known risk
factors for neurodevelopmental disorders, including schizophrenia, autism, and attention …

Epigenetic modifications are increasingly recognized to play a role in the etiology and
pathophysiology of schizophrenia and other psychiatric disorders with developmental …

Prenatal adverse environments, such as maternal stress, toxicological exposures, and viral
infections, can disrupt normal brain development and contribute to neurodevelopmental …

Abstract The British epidemiologist Dr. David J. Barker documented the relationship
between infant birth weight and later onset of hypertension, coronary heart disease, insulin …

Reelin is a glycoprotein that serves important roles both during development (regulation of
neuronal migration and brain lamination) and in adulthood (maintenance of synaptic …