[PDF][PDF] Intrahepatic cholangiocarcinoma: continuing challenges and translational advances
Intrahepatic cholangiocarcinoma (iCCA) has over the last 10‐20 years become the focus of
increasing concern, largely due to its rising incidence and high mortality rates worldwide …
increasing concern, largely due to its rising incidence and high mortality rates worldwide …
The anti-inflammatory effects of vitamin D in tumorigenesis
W Liu, L Zhang, HJ Xu, Y Li, CM Hu, JY Yang… - International journal of …, 2018 - mdpi.com
In conjunction with the classical functions of regulating intestinal, bone, and kidney calcium
and phosphorus absorption, as well as bone mineralization of vitamin D, the population …
and phosphorus absorption, as well as bone mineralization of vitamin D, the population …
The single-cell epigenomic and transcriptional landscape of immunity to influenza vaccination
Emerging evidence indicates a fundamental role for the epigenome in immunity. Here, we
mapped the epigenomic and transcriptional landscape of immunity to influenza vaccination …
mapped the epigenomic and transcriptional landscape of immunity to influenza vaccination …
TLR4 signalling via Piezo1 engages and enhances the macrophage mediated host response during bacterial infection
J Geng, Y Shi, J Zhang, B Yang, P Wang… - Nature …, 2021 - nature.com
TLR4 signaling plays key roles in the innate immune response to microbial infection. Innate
immune cells encounter different mechanical cues in both health and disease to adapt their …
immune cells encounter different mechanical cues in both health and disease to adapt their …
YAP aggravates inflammatory bowel disease by regulating M1/M2 macrophage polarization and gut microbial homeostasis
X Zhou, W Li, S Wang, P Zhang, Q Wang, J Xiao… - Cell reports, 2019 - cell.com
Inflammation, epithelial cell regeneration, macrophage polarization, and gut microbial
homeostasis are critical for the pathological processes associated with inflammatory bowel …
homeostasis are critical for the pathological processes associated with inflammatory bowel …
Macrophage achieves self-protection against oxidative stress-induced ageing through the Mst-Nrf2 axis
P Wang, J Geng, J Gao, H Zhao, J Li, Y Shi… - Nature …, 2019 - nature.com
Reactive oxygen species (ROS) production in phagocytes is a major defense mechanism
against pathogens. However, the cellular self-protective mechanism against such potential …
against pathogens. However, the cellular self-protective mechanism against such potential …
YAP promotes the activation of NLRP3 inflammasome via blocking K27-linked polyubiquitination of NLRP3
D Wang, Y Zhang, X Xu, J Wu, Y Peng, J Li… - Nature …, 2021 - nature.com
The transcription coactivator YAP plays a vital role in Hippo pathway for organ-size control
and tissue homeostasis. Recent studies have demonstrated YAP is closely related to …
and tissue homeostasis. Recent studies have demonstrated YAP is closely related to …
The transcriptional coactivator TAZ regulates reciprocal differentiation of TH17 cells and Treg cells
J Geng, S Yu, H Zhao, X Sun, X Li, P Wang… - Nature …, 2017 - nature.com
An imbalance in the lineages of immunosuppressive regulatory T cells (Treg cells) and the
inflammatory TH17 subset of helper T cells leads to the development of autoimmune and/or …
inflammatory TH17 subset of helper T cells leads to the development of autoimmune and/or …
Red blood cell membrane-camouflaged nanoparticles loaded with AIEgen and Poly (I: C) for enhanced tumoral photodynamic-immunotherapy
J Dai, M Wu, Q Wang, S Ding, X Dong… - National science …, 2021 - academic.oup.com
Red blood cell (RBC)-mimicking nanoparticles (NPs) offer a promising platform for drug
delivery because of their prolonged circulation time, reduced immunogenicity and specific …
delivery because of their prolonged circulation time, reduced immunogenicity and specific …
The crosstalk between hippo-YAP pathway and innate immunity
S Wang, L Zhou, L Ling, X Meng, F Chu… - Frontiers in …, 2020 - frontiersin.org
Recognition of pathogen-associated molecular patterns (PAMPs) triggers expression of
antiviral interferons and proinflammatory cytokines, which functions as the frontier of host …
antiviral interferons and proinflammatory cytokines, which functions as the frontier of host …