Myeloid-derived suppressor cells in the era of increasing myeloid cell diversity
Myeloid-derived suppressor cells (MDSCs) are pathologically activated neutrophils and
monocytes with potent immunosuppressive activity. They are implicated in the regulation of …
monocytes with potent immunosuppressive activity. They are implicated in the regulation of …
The Yin and Yang of myeloid derived suppressor cells
In recent years, most of our knowledge about myeloid derived suppressor cells (MDSCs)
has come from cancer studies, which depicts Yin side of MDSCs. In cancer, inherent …
has come from cancer studies, which depicts Yin side of MDSCs. In cancer, inherent …
Human leukocyte immunoglobulin-like receptors in health and disease
S Redondo-García, C Barritt, C Papagregoriou… - Frontiers in …, 2023 - frontiersin.org
Human leukocyte immunoglobulin (Ig)-like receptors (LILR) are a family of 11 innate
immunomodulatory receptors, primarily expressed on lymphoid and myeloid cells. LILRs are …
immunomodulatory receptors, primarily expressed on lymphoid and myeloid cells. LILRs are …
Leukocyte immunoglobulin-like receptor subfamily B: therapeutic targets in cancer
Inhibitory leukocyte immunoglobulin-like receptors (LILRBs 1–5) transduce signals via
intracellular immunoreceptor tyrosine-based inhibitory motifs that recruit phosphatases to …
intracellular immunoreceptor tyrosine-based inhibitory motifs that recruit phosphatases to …
[HTML][HTML] Role of myeloid-derived suppressor cells in the promotion and immunotherapy of colitis-associated cancer
Y Wang, Y Ding, Y Deng, Y Zheng… - … for Immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Colitis-associated cancer (CAC) is a specific type of colorectal cancer that develops from
inflammatory bowel disease (IBD). Myeloid-derived suppressor cells (MDSCs) are a …
inflammatory bowel disease (IBD). Myeloid-derived suppressor cells (MDSCs) are a …
Myeloid‐derived suppressor cells in the therapy of autoimmune diseases
Myeloid‐derived suppressor cells (MDSCs) are well recognized as critical factors in the
pathology of tumors. However, their roles in autoimmune diseases are still unclear, which …
pathology of tumors. However, their roles in autoimmune diseases are still unclear, which …
Pharmacological modulation of myeloid-derived suppressor cells to dampen inflammation
C van Geffen, C Heiss, A Deißler… - Frontiers in …, 2022 - frontiersin.org
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous cell population with potent
suppressive and regulative properties. MDSCs' strong immunosuppressive potential creates …
suppressive and regulative properties. MDSCs' strong immunosuppressive potential creates …
Myeloid-derived suppressor cells as cellular immunotherapy in transplantation and autoimmune diseases
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature
myeloid cells, which have been characterized for their immunosuppressive capacity through …
myeloid cells, which have been characterized for their immunosuppressive capacity through …
Human inhibitory leukocyte Ig-like receptors: from immunotolerance to immunotherapy
A Roghanian, C De Louche - JCI insight, 2022 - eprints.soton.ac.uk
In recent decades, immunotherapeutic strategies have been used to treat a wide range of
pathologies, many of which were previously incurable, such as cancer and autoimmune …
pathologies, many of which were previously incurable, such as cancer and autoimmune …
Understanding regulatory B cells in autoimmune diseases: the case of multiple sclerosis
BT Cuc, J Pohar, S Fillatreau - Current opinion in immunology, 2019 - Elsevier
Highlights•B cells have regulatory functions in EAE and MS through IL-10 production.•The
differentiation of IL-10-producing B cells is associated to plasmocytes formation.• …
differentiation of IL-10-producing B cells is associated to plasmocytes formation.• …