Immunosuppression modifications based on an immune response assay: results of a randomized, controlled trial

M Ravaioli, F Neri, T Lazzarotto, VR Bertuzzo… - …, 2015 - journals.lww.com
Background An immune function assay shows promise for identifying solid organ recipients
at risk for infection or rejection. The following randomized prospective study was designed to …

Can immune cell function assay identify patients at risk of infection or rejection? A meta-analysis

X Ling, J Xiong, W Liang, PM Schroder, L Wu… - …, 2012 - journals.lww.com
Background. The Cylex ImmuKnow cell function assay (CICFA) is being considered as a
possible tool for identification of infection and rejection in transplant recipients. However, the …

Benefit of immune monitoring in heart transplant patients using ATP production in activated lymphocytes

JA Kobashigawa, KK Kiyosaki, JK Patel… - The Journal of heart and …, 2010 - Elsevier
BACKGROUND: Balancing immunosuppression to prevent rejection while minimizing
infection or drug toxicity risk is a major challenge in heart transplantation. Therapeutic drug …

Immunosuppression for pancreas transplantation with an emphasis on antibody induction strategies: review and perspective

RJ Stratta, AC Farney, J Rogers… - Expert Review of Clinical …, 2014 - Taylor & Francis
A review of recent literature was performed to identify trends and evaluate outcomes with
respect to immunosuppression in pancreas transplantation (PTX). In the past decade, the …

Advances in immunosuppression for pancreas transplantation

RP Singh, RJ Stratta - Current Opinion in Organ Transplantation, 2008 - journals.lww.com
Antibody induction and either tacrolimus/mycophenolate mofetil or tacrolimus/sirolimus
maintenance therapy with steroid withdrawal have become the mainstay of contemporary …

Experience with immune monitoring in lung transplant recipients: correlation of low immune function with infection

S Husain, K Raza, JM Pilewski, D Zaldonis… - …, 2009 - journals.lww.com
Background. Lung transplants, in particular, have the highest rate of infections among solid
organ transplant recipients. However, there is no existing objective measure to predict the …

[PDF][PDF] Using an immune functional assay to differentiate acute cellular rejection from recurrent hepatitis C in liver transplant patients

R Cabrera, M Ararat, C Soldevila‐Pico… - Liver …, 2009 - Wiley Online Library
In transplant recipients transplanted for hepatitis C, presentation of abnormal transaminases
can herald the presentation of recurrent hepatitis C, cellular rejection, or both. Given the …

Individualized immune monitoring of cardiac transplant recipients by noninvasive longitudinal cellular immunity tests

M Israeli, T Ben-Gal, V Yaari, A Valdman, I Matz… - …, 2010 - journals.lww.com
Background. Common immunosuppression strategies after heart transplantation (HTx) are
based on accepted target drug levels, disregarding that drug levels do not correlate with the …

Pretransplant donor-specific and non-specific immune parameters associated with early acute rejection

NL Reinsmoen, KMM Cornett, R Kloehn… - …, 2008 - journals.lww.com
Background. New immunosuppression protocols have resulted in decreased rates of biopsy-
proven acute rejection; however, it is unclear whether recipients without biopsy-proven …

Measurement of CD4+ T‐cell function in predicting allograft rejection and recurrent hepatitis C after liver transplantation

K Hashimoto, C Miller, K Hirose, T Diago… - Clinical …, 2010 - Wiley Online Library
Hashimoto K, Miller C, Hirose K, Diago T, Aucejo F, Quintini C, Eghtesad B, Corey R, Yerian
L, Lopez R, Zein N, Fung J. Measurement of CD4+ T‐cell function in predicting allograft …