Linking chronic periodontitis and oral cancer: A review

A Kavarthapu, K Gurumoorthy - Oral oncology, 2021 - Elsevier
The aim of this article is to survey the accessible writing on the pathogenetic systems
engaged with the relationship between oral malignancy and periodontitis. Gingival tissue …

A review of research on salivary biomarkers for oral cancer detection

YSL Cheng, T Rees, J Wright - Clinical and translational medicine, 2014 - Springer
Using saliva for disease diagnostics and health surveillance is a promising approach as
collecting saliva is relatively easy and non-invasive. Over the past two decades, using …

Comparison of oral microbiota in tumor and non-tumor tissues of patients with oral squamous cell carcinoma

S Pushalkar, X Ji, Y Li, C Estilo, R Yegnanarayana… - BMC microbiology, 2012 - Springer
Background Bacterial infections have been linked to malignancies due to their ability to
induce chronic inflammation. We investigated the association of oral bacteria in oral …

Evaluation of proinflammatory, NF-kappaB dependent cytokines: IL-1α, IL-6, IL-8, and TNF-α in tissue specimens and saliva of patients with oral squamous cell …

K Babiuch, B Kuśnierz-Cabala, B Kęsek… - Journal of Clinical …, 2020 - mdpi.com
Background: Oral squamous cell carcinoma (OSCC) is a life-threatening disease. It could be
preceded by oral potentially malignant disorders (OPMDs). It was confirmed that chronic …

Dysbiosis of salivary microbiome and cytokines influence oral squamous cell carcinoma through inflammation

AK Rai, M Panda, AK Das, T Rahman, R Das… - Archives of …, 2021 - Springer
Advanced combinatorial treatments of surgery, chemotherapy, and radiotherapy do not have
any effect on the enhancement of a 5-year survival rate of oral squamous cell carcinoma …

Saliva–a new opportunity for fluid biopsy

Z Huang, X Yang, Y Huang, Z Tang, Y Chen… - Clinical Chemistry and …, 2023 - degruyter.com
Saliva is a complex biological fluid with a variety of biomolecules, such as DNA, RNA,
proteins, metabolites and microbiota, which can be used for the screening and diagnosis of …

Interleukin‐6 in oral diseases: a review

L Nibali, S Fedele, F D'aiuto, N Donos - Oral diseases, 2012 - Wiley Online Library
Oral Diseases (2012) 18, 236–243 Interleukin‐6 (IL‐6) is a pleomorphic cytokine involved in
a number of physiologic and pathologic processes including response to trauma and …

Salivary biomarker development using genomic, proteomic and metabolomic approaches

NJ Bonne, DTW Wong - Genome medicine, 2012 - Springer
The use of saliva as a diagnostic sample provides a non-invasive, cost-efficient method of
sample collection for disease screening without the need for highly trained professionals …

Interleukin‐6 promotes tumorigenesis by altering DNA methylation in oral cancer cells

JA Gasche, J Hoffmann, CR Boland… - International journal of …, 2011 - Wiley Online Library
Worldwide oral squamous cell carcinoma (OSCC) accounts for more than 100,000 deaths
each year. Chronic inflammation constitutes one of the key risk factors for OSCC …

Inflammatory mediators in oral cancer: pathogenic mechanisms and diagnostic potential

SE Niklander - Frontiers in Oral Health, 2021 - frontiersin.org
Approximately 15% of cancers are attributable to the inflammatory process, and growing
evidence supports an association between oral squamous cell carcinoma (OSCC) and …