During the past two decades, there has been a tremendous expansion of knowledge
regarding the neurobiological effects of substance abuse and how these effects impact …

Psychostimulants abuse is a major public concern because is associated with serious health
complications, including devastating consequences on the central nervous system (CNS) …

Cocaine-responsive gene expression changes have been described after either no drug
abstinence or short periods of abstinence. Little data exist on the persistence of these …

Diabetic retinopathy can result in vision loss and involves progressive neurovascular
degeneration of the retina. This study tested the hypothesis that diabetes decreases the …

Diabetic retinopathy is the leading cause of blindness in working age persons. Targeted
studies have uncovered several components of the pathophysiology of the disease without …

Methamphetamine (METH) is a highly addictive psychostimulant that may cause long-lasting
synaptic dysfunction and abnormal gene expression. We aimed to explore the differential …

Background Many studies of cocaine-responsive gene expression have focused on
changes occurring during cocaine exposure, but few studies have examined the persistence …

In the accompanying paper, we described incubation of heroin-seeking behavior in rats
following 14 days of abstinence. To gain an understanding of genomic changes that …

The use of methamphetamine (METH) is a growing worldwide epidemic that bears grave
societal implications. METH is known to exert its neurotoxic effects on the dopaminergic and …

The adverse effects of amphetamine-(AMPH) and methamphetamine-(METH) induced
hyperthermia on vasculature, peripheral organs and peripheral immune system are …