Biological clocks as age estimation markers in animals: a systematic review and meta‐analysis
LS Le Clercq, A Kotzé, JP Grobler… - Biological …, 2023 - Wiley Online Library
Various biological attributes associated with individual fitness in animals change predictably
over the lifespan of an organism. Therefore, the study of animal ecology and the work of …
over the lifespan of an organism. Therefore, the study of animal ecology and the work of …
A mammalian methylation array for profiling methylation levels at conserved sequences
A Arneson, A Haghani, MJ Thompson… - Nature …, 2022 - nature.com
Infinium methylation arrays are not available for the vast majority of non-human mammals.
Moreover, even if species-specific arrays were available, probe differences between them …
Moreover, even if species-specific arrays were available, probe differences between them …
Universal DNA methylation age across mammalian tissues
Aging, often considered a result of random cellular damage, can be accurately estimated
using DNA methylation profiles, the foundation of pan-tissue epigenetic clocks. Here, we …
using DNA methylation profiles, the foundation of pan-tissue epigenetic clocks. Here, we …
Universal DNA methylation age across mammalian tissues
Aging is often perceived as a degenerative process resulting from random accrual of cellular
damage over time. Despite this, age can be accurately estimated by epigenetic clocks based …
damage over time. Despite this, age can be accurately estimated by epigenetic clocks based …
Harnessing male germline epigenomics for the genetic improvement in cattle
Sperm is essential for successful artificial insemination in dairy cattle, and its quality can be
influenced by both epigenetic modification and epigenetic inheritance. The bovine germline …
influenced by both epigenetic modification and epigenetic inheritance. The bovine germline …
DNA methylation aging and transcriptomic studies in horses
Cytosine methylation patterns have not yet been thoroughly studied in horses. Here, we
profile n= 333 samples from 42 horse tissue types at loci that are highly conserved between …
profile n= 333 samples from 42 horse tissue types at loci that are highly conserved between …
DNA methylation‐based biomarkers for ageing long‐lived cetaceans
Epigenetic approaches for estimating the age of living organisms are revolutionizing studies
of long‐lived species. Molecular biomarkers that allow age estimates from small tissue …
of long‐lived species. Molecular biomarkers that allow age estimates from small tissue …
Multi-tissue DNA methylation aging clocks for sea lions, walruses and seals
Age determination of wild animals, including pinnipeds, is critical for accurate population
assessment and management. For most pinnipeds, current age estimation methodologies …
assessment and management. For most pinnipeds, current age estimation methodologies …
DNA methylation networks underlying mammalian traits
Using DNA methylation profiles (n= 15,456) from 348 mammalian species, we constructed
phyloepigenetic trees that bear marked similarities to traditional phylogenetic ones. Using …
phyloepigenetic trees that bear marked similarities to traditional phylogenetic ones. Using …
Epigenetic aging in cows is accelerated by milk production
ABSTRACT DNA methylation has proven to be the most promising age-predictive biomarker
in mammals resulting in the emergence of 'epigenetic clocks' that describe the relationship …
in mammals resulting in the emergence of 'epigenetic clocks' that describe the relationship …