Immunosuppression is a hallmark of pancreatic ductal adenocarcinoma (PDAC),
contributing to early metastasis and poor patient survival. Compared to the localized tumors …

Cell culture encompasses procedures for extracting cells from their natural tissue and
cultivating them under controlled artificial conditions. During this process, various factors …

The efficacy and safety of chimeric antigen receptor (CAR) T cell therapy is still inconclusive
in solid tumor treatment. Recently, nanotechnology has emerged as a potent strategy to …

Organ-on-chip (OoC) technology bridges the principles of biology and engineering to create
a new generation of in vitro models and involves highly interdisciplinary collaboration across …

Precision radiotherapy, such as targeted radioligand therapy, accentuates the precise
delivery of radiation to tumor cells while limiting radiation damage to surrounding normal …

Introduction: Organ-on-chips have become an effective platform for studying the physiology
of tissues and organs and for evaluating the safety and efficacy of drugs. In these systems …

The tumor microenvironment (TME) comprises a diverse array of cells, both cancerous and
non-cancerous, including stromal cells and immune cells. Complex interactions among …

Acute and requiring attention problem of oncotheranostics is a necessity for the urgent
development of operative and precise diagnostics methods, followed by efficient therapy, to …

The therapeutic modes of cancers have been profoundly renovated by immunotherapies,
which have shown extraordinary treating efficacy in certain tumor entities. However, the …

Cancer treatment strategies such as Anti-programmed death-ligand 1 (Anti-PD-L1) or
chimeric antigen receptors (CAR) T-cells are limited by low objective response rates and …