The proteoglycan superfamily now contains more than 30 full-time molecules that fulfill a
variety of biological functions. Proteoglycans act as tissue organizers, influence cell growth …

CpG islands are short stretches of CpG rich regions that are frequently associated with the
promoter region of genes. Aberrant methylation of CpG islands is one mechanism of …

CpG island methylation has been linked to tumor suppressor gene inactivation in neoplasia
and may serve as a useful marker to clone novel cancer-related genes. We have developed …

The retinoblastoma susceptibility gene is a tumour suppressor and its product
retinoblastoma protein (pRb) has been known for 10 years as a repressor of progression …

Master regulator genes (MRGs) have become a hot topic in recent decades. They not only
affect the development of tissue and organ systems but also play a role in other signal …

Proteoglycans consist of a core protein and an associated glycosaminoglycan (GAG) 4
chain of heparan sulfate, chondroitin sulfate, dermatan sulfate or keratan sulfate, which are …

The functions of p107 and p130, members of the retinoblastoma family, include the control of
cell cycle progression and differentiation in several tissues. Our previous studies suggested …

The dihydrofolate reductase (dhfr) promoter is powerfully activated by the transcription factor
Sp1. It has been suggested that Sp1 is a potential target for transcriptional regulation by the …

US6261770B1 - Method to clone mRNAs - Google Patents US6261770B1 - Method to clone
mRNAs - Google Patents Method to clone mRNAs Download PDF Info Publication number …

Abstract pRB is required for IFN-γ-induction of MHC class II in human tumor cell lines,
providing a potential link between tumor suppressors and the immune system. However …