The incidence of inflammatory bowel disease (IBD) is rapidly rising throughout the world.
Although tremendous efforts have been made, limited therapeutics are available for IBD …

Site-specific colon drug delivery is a practical approach for the treatment of local diseases of
the colon with several advantages such as rapid onset of action and reduction of the dosage …

In many respects, polymeric materials have a preeminent position among excipients, as they
form the backbone of modern pharmaceutical formulation practice and drug delivery …

Single pH-dependent drug delivery systems have been widely used for colon-targeted
delivery, but their efficiency is often hampered by the variation in gut pH. To overcome the …

Abstract Formulation design for colon-specific delivery of 5-aminosalicylic acid (5-ASA)
could bring some therapeutic benefits in the treatment of ulcerative colitis (UC). In the current …

Osteogenesis surrounding dental implants is initiated by a series of early physiological
events, including the inflammatory response. However, the persistence of an anti-infection …

The aim of this study was to evaluate and optimize the combination of time and pH-
dependent polymers as a single coating for the design of the colon-specific drug delivery …

Oral colon delivery is pursued through a number of formulation strategies with the aim of
enabling effective and well-tolerated treatments for large bowel pathologies or enhancing …

Most pH-sensitive polymer coating studies for potential colonic delivery systems apply
multiple layers to protect the active agent from degradation and early release in the stomach …

In the last two decades colon targeted drug delivery has gained increased importance not
just for the deliver drugs for the treatment of various colonic diseases but also for its potential …