Increasing attention has been focused on the study of protein–metabolite interactions (PMI),
which play a key role in regulating protein functions and directing an orchestra of cellular …

Overproduction of the exopolysaccharide alginate contributes to the pathogenicity and
antibiotic tolerance of Pseudomonas aeruginosa in chronic infections. The second …

Most naturally competent bacteria tightly regulate the window of the competent state to
maximize their ecological fitness under specific conditions. Development of competence by …

The bacterial stringent response involves wide-ranging metabolic reprogramming aimed at
increasing long-term survivability during stress conditions. One of the hallmarks of the …

Natural competence is an important means of horizontal gene transfer that bacteria use to
gain new physiological traits such as multiple drug resistance. Most naturally competent …