Oxytocin, neural plasticity, and social behavior

RC Froemke, LJ Young - Annual Review of Neuroscience, 2021 - annualreviews.org
Oxytocin regulates parturition, lactation, parental nurturing, and many other social behaviors
in both sexes. The circuit mechanisms by which oxytocin modulates social behavior are …

The oxytocin receptor: from intracellular signaling to behavior

B Jurek, ID Neumann - Physiological reviews, 2018 - journals.physiology.org
The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …

Oxytocin, vasopressin, and social behavior: from neural circuits to clinical opportunities

N Rigney, GJ de Vries, A Petrulis, LJ Young - Endocrinology, 2022 - academic.oup.com
Oxytocin and vasopressin are peptide hormones secreted from the pituitary that are well
known for their peripheral endocrine effects on childbirth/nursing and blood pressure/urine …

The neural mechanisms and circuitry of the pair bond

H Walum, LJ Young - Nature Reviews Neuroscience, 2018 - nature.com
Love is one of our most powerful emotions, inspiring some of the greatest art, literature and
conquests of human history. Although aspects of love are surely unique to our species …

Neural mechanisms of mother–infant bonding and pair bonding: Similarities, differences, and broader implications

M Numan, LJ Young - Hormones and behavior, 2016 - Elsevier
This article is part of a Special Issue “Parental Care”. Mother–infant bonding is a
characteristic of virtually all mammals. The maternal neural system may have provided the …

Statistical and methodological considerations for the interpretation of intranasal oxytocin studies

H Walum, ID Waldman, LJ Young - Biological psychiatry, 2016 - Elsevier
Over the last decade, oxytocin (OT) has received focus in numerous studies associating
intranasal administration of this peptide with various aspects of human social behavior …

Oxytocin and vasopressin neural networks: Implications for social behavioral diversity and translational neuroscience

ZV Johnson, LJ Young - Neuroscience & Biobehavioral Reviews, 2017 - Elsevier
Oxytocin-and vasopressin-related systems are present in invertebrate and vertebrate
bilaterian animals, including humans, and exhibit conserved neuroanatomical and …

Oxytocin and social relationships: from attachment to bond disruption

OJ Bosch, LJ Young - Behavioral pharmacology of neuropeptides …, 2018 - Springer
Social relationships throughout life are vital for well-being and physical and mental health. A
significant amount of research in animal models as well as in humans suggests that oxytocin …

Can oxytocin treat autism?

LJ Young, CE Barrett - Science, 2015 - science.org
The US Centers for Disease Control and Prevention estimates the prevalence of autism
spectrum disorders (ASDs) to be 1 in 68 children in the United States, yet no drugs to treat …

Social stimuli induce activation of oxytocin neurons within the paraventricular nucleus of the hypothalamus to promote social behavior in male mice

SL Resendez, VMK Namboodiri, JM Otis… - Journal of …, 2020 - Soc Neuroscience
Oxytocin (OT) is critical for the expression of social behavior across a wide array of species;
however, the role of this system in the encoding of socially relevant information is not well …