HTLV-1, the other pathogenic yet neglected human retrovirus: from transmission to therapeutic treatment
N Futsch, R Mahieux, H Dutartre - Viruses, 2017 - mdpi.com
Going back to their discovery in the early 1980s, both the Human T-cell Leukemia virus type-
1 (HTLV-1) and the Human Immunodeficiency Virus type-1 (HIV-1) greatly fascinated the …
1 (HTLV-1) and the Human Immunodeficiency Virus type-1 (HIV-1) greatly fascinated the …
CC chemokine receptor 7 in cancer
CA Bill, CM Allen, CM Vines - Cells, 2022 - mdpi.com
CC chemokine receptor 7 (CCR7) was one of the first two chemokine receptors that were
found to be upregulated in breast cancers. Chemokine receptors promote chemotaxis of …
found to be upregulated in breast cancers. Chemokine receptors promote chemotaxis of …
HTLV-1 infection promotes excessive T cell activation and transformation into adult T cell leukemia/lymphoma
Human T cell leukemia virus type 1 (HTLV-1) mainly infects CD4+ T cells and induces
chronic, persistent infection in infected individuals, with some developing adult T cell …
chronic, persistent infection in infected individuals, with some developing adult T cell …
The Role of Chemokines in the Pathogenesis of HTLV-1
R Zargari, M Mahdifar, A Mohammadi… - Frontiers in …, 2020 - frontiersin.org
Human T cell leukemia virus type 1 (HTLV-1) is a human retrovirus that is associated with
two main diseases: HTLV-associated myelopathy/tropical spastic paraparesis (HAM/TSP) …
two main diseases: HTLV-associated myelopathy/tropical spastic paraparesis (HAM/TSP) …
CCR7 as a novel therapeutic target in t-cell PROLYMPHOCYTIC leukemia
C Cuesta-Mateos, P Fuentes, A Schrader… - Biomarker …, 2020 - Springer
T-cell prolymphocytic leukemia (T-PLL) is a poor prognostic disease with very limited
options of efficient therapies. Most patients are refractory to chemotherapies and despite …
options of efficient therapies. Most patients are refractory to chemotherapies and despite …
[PDF][PDF] CCR7 in blood cancers–review of its pathophysiological roles and the potential as a therapeutic target
C Cuesta-Mateos, F Terrón, M Herling - Frontiers in Oncology, 2021 - frontiersin.org
According to the classical paradigm, CCR7 is a homing chemokine receptor that grants
normal lymphocytes access to secondary lymphoid tissues such as lymph nodes or spleen …
normal lymphocytes access to secondary lymphoid tissues such as lymph nodes or spleen …
The role of post-translational modifications of chemokines by CD26 in cancer
A De Zutter, J Van Damme, S Struyf - Cancers, 2021 - mdpi.com
Simple Summary Chemokines are central players in cancer and can be post-translationally
modified by dipeptidyl peptidase IV (DPPIV)/CD26. This can have different effects on …
modified by dipeptidyl peptidase IV (DPPIV)/CD26. This can have different effects on …
Switching and loss of cellular cytokine producing capacity characterize in vivo viral infection and malignant transformation in human T- lymphotropic virus type 1 …
Adult T-cell leukaemia/lymphoma (ATL) arises from chronic non-malignant human T
lymphotropic virus type-1 (HTLV-1) infection which is characterized by high plasma pro …
lymphotropic virus type-1 (HTLV-1) infection which is characterized by high plasma pro …
Quantification of T cell clonality in human T cell leukaemia virus type-1 carriers can detect the development of adult T cell leukaemia early
Adult T cell leukaemia/lymphoma (ATL) arises from clonally expanded T cells that are
infected with human T cell leukaemia virus type-1 (HTLV-1). Here, we show that ATL can be …
infected with human T cell leukaemia virus type-1 (HTLV-1). Here, we show that ATL can be …
The chemokine system in oncogenic pathways driven by viruses: perspectives for cancer immunotherapy
G Schlecht-Louf, C Deback, F Bachelerie - Cancers, 2022 - mdpi.com
Simple Summary Oncoviruses are viruses with oncogenic potential, responsible for almost
20% of human cancers worldwide. They are from various families, some of which belong to …
20% of human cancers worldwide. They are from various families, some of which belong to …