[HTML][HTML] The genotype-tissue expression (GTEx) project
J Lonsdale, J Thomas, M Salvatore, R Phillips, E Lo… - Nature …, 2013 - nature.com
Genome-wide association studies have identified thousands of loci for common diseases,
but, for the majority of these, the mechanisms underlying disease susceptibility remain …
but, for the majority of these, the mechanisms underlying disease susceptibility remain …
Soluble starch synthase enzymes in cereals: An updated review
A Irshad, H Guo, SU Rehman, X Wang, C Wang… - Agronomy, 2021 - mdpi.com
Cereal crops have starch in their endosperm, which has provided calories to humans and
livestock since the dawn of civilization to the present day. Starch is one of the important …
livestock since the dawn of civilization to the present day. Starch is one of the important …
Genetics of gene expression in immunity to infection
BP Fairfax, JC Knight - Current opinion in immunology, 2014 - Elsevier
Highlights•Mapping gene expression as a quantitative trait resolves functional regulatory
genetic variants.•Genomic modulators of immune gene expression are typically context …
genetic variants.•Genomic modulators of immune gene expression are typically context …
Impact of microRNA regulation on variation in human gene expression
MicroRNAs (miRNAs) are endogenously expressed small RNAs that regulate expression of
mRNAs at the post-transcriptional level. The consequence of miRNA regulation is …
mRNAs at the post-transcriptional level. The consequence of miRNA regulation is …
Genome-wide identification of microRNA expression quantitative trait loci
Identification of microRNA expression quantitative trait loci (miR-eQTL) can yield insights
into regulatory mechanisms of microRNA transcription, and can help elucidate the role of …
into regulatory mechanisms of microRNA transcription, and can help elucidate the role of …
Mapping genetic contributions to cardiac pathology induced by Beta-adrenergic stimulation in mice
Background—Chronic stress-induced cardiac pathology exhibits both a wide range in
severity and a high degree of heterogeneity in clinical manifestation in human patients. This …
severity and a high degree of heterogeneity in clinical manifestation in human patients. This …
Genome-wide analysis implicates microRNAs and their target genes in the development of bipolar disorder
AJ Forstner, A Hofmann, A Maaser, S Sumer… - Translational …, 2015 - nature.com
Bipolar disorder (BD) is a severe and highly heritable neuropsychiatric disorder with a
lifetime prevalence of 1%. Molecular genetic studies have identified the first BD susceptibility …
lifetime prevalence of 1%. Molecular genetic studies have identified the first BD susceptibility …
Genetic regulation of human adipose microRNA expression and its consequences for metabolic traits
M Civelek, R Hagopian, C Pan, N Che… - Human molecular …, 2013 - academic.oup.com
The genetics of messenger RNA (mRNA) expression has been extensively studied in
humans and other organisms, but little is known about genetic factors contributing to …
humans and other organisms, but little is known about genetic factors contributing to …
Dissecting the roles of microRNAs in coronary heart disease via integrative genomic analyses
Objective—The roles of microRNAs (miRNAs) in coronary heart disease (CHD) have not
been well characterized. This study sought to systematically characterize the complex …
been well characterized. This study sought to systematically characterize the complex …
A genomic portrait of the genetic architecture and regulatory impact of microRNA expression in response to infection
KJ Siddle, M Deschamps, L Tailleux… - Genome …, 2014 - genome.cshlp.org
MicroRNAs (miRNAs) are critical regulators of gene expression, and their role in a wide
variety of biological processes, including host antimicrobial defense, is increasingly well …
variety of biological processes, including host antimicrobial defense, is increasingly well …