Genome-wide association studies have identified thousands of loci for common diseases,
but, for the majority of these, the mechanisms underlying disease susceptibility remain …

Cereal crops have starch in their endosperm, which has provided calories to humans and
livestock since the dawn of civilization to the present day. Starch is one of the important …

Highlights•Mapping gene expression as a quantitative trait resolves functional regulatory
genetic variants.•Genomic modulators of immune gene expression are typically context …

MicroRNAs (miRNAs) are endogenously expressed small RNAs that regulate expression of
mRNAs at the post-transcriptional level. The consequence of miRNA regulation is …

Identification of microRNA expression quantitative trait loci (miR-eQTL) can yield insights
into regulatory mechanisms of microRNA transcription, and can help elucidate the role of …

Background—Chronic stress-induced cardiac pathology exhibits both a wide range in
severity and a high degree of heterogeneity in clinical manifestation in human patients. This …

Bipolar disorder (BD) is a severe and highly heritable neuropsychiatric disorder with a
lifetime prevalence of 1%. Molecular genetic studies have identified the first BD susceptibility …

The genetics of messenger RNA (mRNA) expression has been extensively studied in
humans and other organisms, but little is known about genetic factors contributing to …

Objective—The roles of microRNAs (miRNAs) in coronary heart disease (CHD) have not
been well characterized. This study sought to systematically characterize the complex …

MicroRNAs (miRNAs) are critical regulators of gene expression, and their role in a wide
variety of biological processes, including host antimicrobial defense, is increasingly well …