Recent developments in 1, 6-addition reactions of para-quinone methides (p-QMs)

JY Wang, WJ Hao, SJ Tu, B Jiang - Organic Chemistry Frontiers, 2020 - pubs.rsc.org
In recent years, para-quinone methides (p-QMs) have emerged as attractive and versatile
synthons in organic synthesis owing to their high reactivity. Consequently, p-QM chemistry …

para‐Quinone Methides as Acceptors in 1,6‐Nucleophilic Conjugate Addition Reactions for the Synthesis of Structurally Diverse Molecules

CGS Lima, FP Pauli, DCS Costa… - European Journal of …, 2020 - Wiley Online Library
para‐Quinone methides (p‐QMs) are naturally occurring molecules that have been finding
increasing synthetic applications in the last few years. The presence of two electronically …

Copper-catalyzed asymmetric 1, 6-conjugate addition of in situ generated para-quinone methides with β-ketoesters

YF Wang, CJ Wang, QZ Feng, JJ Zhai, SS Qi… - Chemical …, 2022 - pubs.rsc.org
A Cu-catalyzed asymmetric 1, 6-conjugate addition of in situ generated para-quinone
methides (p-QMs) with β-ketoester has been developed to construct a ketoester skeleton …

Visible-Light-Catalyzed Tandem Radical Addition/1, 5-Hydrogen Atom Transfer/Cyclization of 2-Alkynylarylethers with Sulfonyl Chlorides

L Li, JZ Li, YB Sun, CM Luo, H Qiu, K Tang, H Liu… - Organic …, 2022 - ACS Publications
A novel visible-light-catalyzed tandem radical addition/1, 5-hydrogen atom
transfer/cyclization cascade of 2-alkynylarylethers with sulfonyl chlorides in 2 …

Stereodivergent synthesis of enantioenriched 2, 3-disubstituted dihydrobenzofurans via a one-pot C–H functionalization/oxa-michael addition cascade

DX Zhu, JG Liu, MH Xu - Journal of the American Chemical …, 2021 - ACS Publications
A one-pot rhodium-catalyzed C–H functionalization/organocatalyzed oxa-Michael addition
cascade reaction has been developed. This methodology enables the stereodivergent …

Construction of Oxygen‐ and Nitrogen‐based Heterocycles from p‐Quinone Methides

G Singh, R Pandey, YA Pankhade, S Fatma… - The Chemical …, 2021 - Wiley Online Library
In the last few years, there has been an explosive growth in the area of para‐quinone
methide (p‐QM) chemistry. This boom is actually due to the unique reactivity pattern of p …

Design and Application of Peptide‐Mimic Phosphonium Salt Catalysts in Asymmetric Synthesis

S Fang, Z Liu, T Wang - Angewandte Chemie International …, 2023 - Wiley Online Library
Chiral phosphonium salt catalysis, traditionally classified as a type of phase transfer
catalysis, has proven to be a powerful strategy for the stereoselective preparation of diverse …

Visible light and base promoted OH insertion/cyclization of para-quinone methides with aryl diazoacetates: An approach to 2, 3-dihydrobenzofuran derivatives

S Zhou, B Cai, C Hu, X Cheng, L Li, J Xuan - Chinese Chemical Letters, 2021 - Elsevier
A visible light and base promoted OH insertion/cyclization of para-quinone methides with
aryl diazoacetates is developed. This one-pot two step reaction offers a mild and efficient …

An access to highly functionalized dihydrobenzofuran spirooxindole scaffolds

D Wang, J Sun, Y Han, Q Sun, CG Yan - Organic Letters, 2022 - ACS Publications
We have developed an efficient protocol for the construction of polycyclic dihydrobenzofuran
spirooxindole scaffolds via base promoted cascade annulation of Morita–Baylis–Hillman …

Recent development in asymmetric organocatalytic domino reactions involving 1, 6-addition as a key step

Y Hussain, M Sharma, A Kumar… - Organic Chemistry …, 2022 - pubs.rsc.org
Due to their unique activation modes, small organic molecule catalysts (organocatalysts)
have proved their potential in facilitating the remote functionalizations of unsaturated …