Developing oncolytic viruses for the treatment of cervical cancer
Cervical cancer represents one of the most important malignancies among women
worldwide. Current therapeutic approaches for cervical cancer are reported not only to be …
worldwide. Current therapeutic approaches for cervical cancer are reported not only to be …
Novel insights into epigenetic drivers of oropharyngeal squamous cell carcinoma: role of HPV and lifestyle factors
P Boscolo-Rizzo, C Furlan, V Lupato, J Polesel… - Clinical …, 2017 - Springer
In the last years, the explosion of high throughput sequencing technologies has enabled
epigenome-wide analyses, allowing a more comprehensive overview of the oropharyngeal …
epigenome-wide analyses, allowing a more comprehensive overview of the oropharyngeal …
Regulation of innate immune responses by cell death‐associated caspases during virus infection
Y Fang, K Peng - The FEBS Journal, 2022 - Wiley Online Library
Viruses are obligate intracellular pathogens that rely on cellular machinery for successful
replication and dissemination. The host cells encode a number of different strategies to …
replication and dissemination. The host cells encode a number of different strategies to …
Expression of E8^E2 Is Required for Wart Formation by Mouse Papillomavirus 1 In Vivo
F Stubenrauch, E Straub, K Klein, D Kramer… - Journal of …, 2021 - Am Soc Microbiol
Human papillomavirus (HPV) E1 and E2 proteins activate genome replication. E2 also
modulates viral gene expression and is involved in the segregation of viral genomes. In …
modulates viral gene expression and is involved in the segregation of viral genomes. In …
Intratype variants of the E2 protein from human papillomavirus type 18 induce different gene expression profiles associated with apoptosis and cell proliferation
AM Fuentes-González, JO Muñoz-Bello… - Archives of …, 2019 - Springer
Persistent infections with high-risk human papillomaviruses (HR-HPVs) are linked to the
development of cervical cancer due to a deregulation of the productive viral cycle in the host …
development of cervical cancer due to a deregulation of the productive viral cycle in the host …
Securin overexpression correlates with the activated Rb/E2F1 pathway and histone H3 epigenetic modifications in raw areca nut-induced carcinogenesis in mice
Background Raw areca nut (RAN) consumption induces oral, esophageal and gastric
cancers, which are significantly associated with the overexpression of pituitary tumor …
cancers, which are significantly associated with the overexpression of pituitary tumor …
Focal Adhesion Kinase Binds to the HPV E2 Protein to Regulate Initial Replication after Infection
L Jose, J Gonzalez, E Kessinger, EJ Androphy… - Pathogens, 2023 - mdpi.com
Human papillomaviruses are small DNA tumor viruses that infect cutaneous and mucosal
epithelia. The viral lifecycle is linked to the differentiation status of the epithelium. During …
epithelia. The viral lifecycle is linked to the differentiation status of the epithelium. During …
HPV E2, E5 致癌机制及相关疫苗研究进展
崔湘杰, 史荔, 陶玉芬 - 中华疾病控制杂志, 2024 - zhjbkz.ahmu.edu.cn
宫颈癌是影响女性的常见恶性肿瘤之一, 其中高危型HPV 的持续感染是导致宫颈癌的主要病因.
在宫颈癌的发生发展过程中, 除了HPV E6, E7 与宫颈癌病变有主要的关系外 …
在宫颈癌的发生发展过程中, 除了HPV E6, E7 与宫颈癌病变有主要的关系外 …
HPV16 E2 variants correlated with radiotherapy treatment and biological significance in cervical cell carcinoma
S Kahla, S Hammami, L Kochbati, MB Chanoufi… - Infection, Genetics and …, 2018 - Elsevier
Specific genetic mutations in human papillomavirus type 16 (HPV16) DNA are considered
important in cervical lesion progression. This study analyzes to what extent radiotherapy …
important in cervical lesion progression. This study analyzes to what extent radiotherapy …
Research progress in the study of HPV E2, E5 oncogenic mechanism and related vaccine
CUI Xiangjie, SHI Li, TAO Yufen - 中华疾病控制杂志, 2024 - zhjbkz.ahmu.edu.cn
Cervical cancer is one of the common malignancies affecting women worldwide, of which
persistent infection with high-risk human papillomavirus (HPV) is the main cause. In the …
persistent infection with high-risk human papillomavirus (HPV) is the main cause. In the …