Circular RNAs (circRNAs) are a novel class of RNAs distinguished by their single-stranded,
covalently-closed topology. Although initially perceived as rare byproducts of aberrant …

CircRNAs are a class of single-stranded RNAs with covalently linked head-to-tail topology.
In the decades since its initial discovery, their biogenesis, regulation, and function have …

Circular RNA (circRNA) is a unique type of noncoding RNA molecule. Compared with
traditional linear RNA, circRNA is a covalently closed circle produced by a process called …

Circular RNAs are an unusual class of single-stranded RNAs whose ends are covalently
linked via back-splicing. Due to their versatility, the need to express circular RNAs in vivo …

Background Insulin like growth factor II mRNA binding protein 3 (IGF2BP3) is an RNA
binding protein with multiple roles in regulation of gene expression at the post …

Neoantigen is a protein produced by mutant gene, which is only expressed in tumor cells. It
is an ideal target for therapeutic tumor vaccines. Although synthetic long peptide (SLP) …

Messenger ribonucleic acid (mRNA) vaccines made their successful public debut in the
effort against the COVID‐19 outbreak starting in late 2019, although the history of mRNA …

Circular RNAs (circRNAs) are a unique class of single-stranded RNA molecules that are
covalently closed and lack 5 and 3 ends. They were first discovered in eukaryotic cells> 30 …

Delivering synthetic protein-coding RNA bypassing the DNA stage for ectopic protein
functioning is a novel therapeutic strategy. Joining the linear RNA head-to-tail covalently …

Circular RNA (circRNA) forms closed loops via back-splicing in precursor mRNA, resisting
exonuclease degradation. In higher eukaryotes, protein-coding genes create circRNAs …