Over the past few decades, substantial evidence has convincingly revealed the existence of
cancer stem cells (CSCs) as a minor subpopulation in cancers, contributing to an aberrantly …

In view of the advancement in the understanding about the most diverse types of cancer and
consequently a relentless search for a cure and increased survival rates of cancer patients …

Cell death resistance is a key feature of tumor cells. One of the main anticancer therapies is
increasing the susceptibility of cells to death. Cancer cells have developed a capability of …

Triple-negative breast cancer (TNBC) is a heterogeneous disease with poorer outcomes
compared to other breast cancer subtypes. Contributing to the worse prognosis in TNBC is …

Recently, cytokine-based pro-tumourigenic signalling has been found to play a major role in
the immune system's pro-tumourigenic activity. On the other hand, other recent findings have …

Glioblastoma (GBM) is an immunosuppressive, lethal brain tumor. Despite advances in
molecular understanding and therapies, the clinical benefits have remained limited, and the …

As cancer immunotherapy continues to benefit from novel approaches which cut immune
'brake pedals'(eg anti-PD1 and anti-CTLA4 antibodies) and push immune cell gas pedals …

Abstract Background Tumour-associated macrophages (TAMs) are often implicated in
cancer progression but can also exert anti-tumour activities. Selective eradication of cancer …

Vascular mimicry is induced by a wide array of genes with functions related to cancer
stemness, hypoxia, angiogenesis and autophagy. Vascular mimicry competent (VM …

Oncolytic virus therapy is a promising new option for cancer. It utilizes genetically
engineered or naturally occurring viruses that selectively replicate in and kill cancer cells …