Oxidative stress and the pathogenesis of neurodegenerative disorders
A Reynolds, C Laurie, RL Mosley… - International review of …, 2007 - Elsevier
Microglia‐derived inflammatory neurotoxins play a principal role in the pathogenesis of
neurodegenerative disorders including Alzheimer's disease, Parkinson's disease …
neurodegenerative disorders including Alzheimer's disease, Parkinson's disease …
Cells of the central nervous system as targets and reservoirs of the human immunodeficiency virus
S Kramer-Hämmerle, I Rothenaigner, H Wolff, JE Bell… - Virus research, 2005 - Elsevier
The availability of highly active antiretroviral therapies (HAART) has not eliminated HIV-1
infection of the central nervous system (CNS) or the occurrence of HIV-associated …
infection of the central nervous system (CNS) or the occurrence of HIV-associated …
Current understanding of HIV-associated neurocognitive disorders pathogenesis
P Gannon, MZ Khan, DL Kolson - Current opinion in neurology, 2011 - journals.lww.com
Prevention and treatment of HAND requires strategies aimed at suppressing CNS HIV
replication and effects of systemic and CNS inflammation in aging and substance-abusing …
replication and effects of systemic and CNS inflammation in aging and substance-abusing …
Nanomedicine in the diagnosis and therapy of neurodegenerative disorders
AV Kabanov, HE Gendelman - Progress in polymer science, 2007 - Elsevier
Neurodegenerative and infectious disorders including Alzheimer's and Parkinson's
diseases, amyotrophic lateral sclerosis, and stroke are rapidly increasing as population's …
diseases, amyotrophic lateral sclerosis, and stroke are rapidly increasing as population's …
Cerebrospinal fluid neopterin: an informative biomarker of central nervous system immune activation in HIV-1 infection
HIV-1 invades the central nervous system (CNS) in the context of acute infection, persists
thereafter in the absence of treatment, and leads to chronic intrathecal immunoactivation that …
thereafter in the absence of treatment, and leads to chronic intrathecal immunoactivation that …
Adriamycin-induced, TNF-α-mediated central nervous system toxicity
The clinical effectiveness of adriamycin (ADR), a potent chemotherapeutic, is known to be
limited by severe cardiotoxic side effects. However, the effect of ADR on brain tissue is not …
limited by severe cardiotoxic side effects. However, the effect of ADR on brain tissue is not …
Macrophage delivery of nanoformulated antiretroviral drug to the brain in a murine model of neuroAIDS
H Dou, CB Grotepas, JEM McMillan… - The Journal of …, 2009 - journals.aai.org
Antiretroviral therapy (ART) shows variable blood-brain barrier penetration. This may affect
the development of neurological complications of HIV infection. In attempts to attenuate viral …
the development of neurological complications of HIV infection. In attempts to attenuate viral …
HIV-1 associated dementia: symptoms and causes
Despite the use of highly active antiretroviral therapy (HAART), neuronal cell death remains
a problem that is frequently found in the brains of HIV-1-infected patients. HAART has …
a problem that is frequently found in the brains of HIV-1-infected patients. HAART has …
The neuropathology of HIV/AIDS
IC Anthony, PJE Bell - International review of psychiatry, 2008 - Taylor & Francis
The introduction of Highly Active Anti-retroviral Therapy (HAART) has resulted in significant
decreases in morbidity and mortality for subjects infected with HIV. The brain is a major …
decreases in morbidity and mortality for subjects infected with HIV. The brain is a major …
HIV effects on age-associated neurocognitive dysfunction: premature cognitive aging or neurodegenerative disease?
RA Cohen, TR Seider, B Navia - Alzheimer's research & therapy, 2015 - Springer
Marked improvements in survival and health outcome for people infected with HIV have
occurred since the advent of combination antiretroviral therapy over a decade ago. Yet HIV …
occurred since the advent of combination antiretroviral therapy over a decade ago. Yet HIV …