Computational modeling of cardiac hemodynamics: current status and future outlook

R Mittal, JH Seo, V Vedula, YJ Choi, H Liu… - Journal of …, 2016 - Elsevier
The proliferation of four-dimensional imaging technologies, increasing computational
speeds, improved simulation algorithms, and the widespread availability of powerful …

Heart blood flow simulation: a perspective review

SN Doost, D Ghista, B Su, L Zhong… - Biomedical engineering …, 2016 - Springer
Cardiovascular disease (CVD), the leading cause of death today, incorporates a wide range
of cardiovascular system malfunctions that affect heart functionality. It is believed that the …

Integrated heart—coupling multiscale and multiphysics models for the simulation of the cardiac function

A Quarteroni, T Lassila, S Rossi… - Computer Methods in …, 2017 - Elsevier
Mathematical modeling of the human heart and its function can expand our understanding of
various cardiac diseases, which remain the most common cause of death in the developed …

Image-based large-eddy simulation in a realistic left heart

C Chnafa, S Mendez, F Nicoud - Computers & Fluids, 2014 - Elsevier
A numerical framework allowing insight in fluid dynamics inside patient-specific human
hearts is presented. The heart cavities and their wall dynamics are extracted from medical …

Application of patient-specific computational fluid dynamics in coronary and intra-cardiac flow simulations: Challenges and opportunities

L Zhong, JM Zhang, B Su, RS Tan, JC Allen… - Frontiers in …, 2018 - frontiersin.org
The emergence of new cardiac diagnostics and therapeutics of the heart has given rise to
the challenging field of virtual design and testing of technologies in a patient-specific …

[HTML][HTML] Vortex flow during early and late left ventricular filling in normal subjects: quantitative characterization using retrospectively-gated 4D flow cardiovascular …

MSM Elbaz, EE Calkoen, JJM Westenberg… - Journal of …, 2014 - Elsevier
Background LV diastolic vortex formation has been suggested to critically contribute to
efficient blood pumping function, while altered vortex formation has been associated with LV …

The effect of inlet and outlet boundary conditions in image-based CFD modeling of aortic flow

S Madhavan, EMC Kemmerling - Biomedical engineering online, 2018 - Springer
Background Computational modeling of cardiovascular flow is a growing and useful field,
but such simulations usually require the researcher to guess the flow's inlet and outlet …

Toward patient-specific simulations of cardiac valves: state-of-the-art and future directions

E Votta, TB Le, M Stevanella, L Fusini, EG Caiani… - Journal of …, 2013 - Elsevier
Recent computational methods enabling patient-specific simulations of native and prosthetic
heart valves are reviewed. Emphasis is placed on two critical components of such …

Vortex ring formation in the left ventricle of the heart: analysis by 4D flow MRI and Lagrangian coherent structures

J Töger, M Kanski, M Carlsson, SJ Kovács… - Annals of biomedical …, 2012 - Springer
Recent studies suggest that vortex ring formation during left ventricular (LV) rapid filling is an
optimized mechanism for blood transport, and that the volume of the vortex ring is an …

Non‐Newtonian blood rheology impacts left atrial stasis in patient‐specific simulations

A Gonzalo, M García‐Villalba, L Rossini… - … journal for numerical …, 2022 - Wiley Online Library
The lack of mechanically effective contraction of the left atrium (LA) during atrial fibrillation
(AF) disturbs blood flow, increasing the risk of thrombosis and ischemic stroke. Thrombosis …