Vascular smooth muscle cells (VSMCs) are the fundamental component of the medial layer
of arteries and are essential for arterial physiology and pathology. It is becoming …

Runx2 is a master transcription factor for osteogenesis. The most important phenomenon
that makes this protein a master regulator for osteogenesis is its structural integrity. In …

Epidemiological and experimental studies have consistently linked alcoholic beverage
consumption with the development of several chronic disorders, such as cancer …

Background Sclerostin is an inhibitor of the Wnt/b-catenin pathway, which regulates bone
formation, and can be expressed in vascular smooth muscle cells (VSMCs). Type 2 diabetes …

Objective Heavy alcohol consumption causes several organic complications, including
vessel wall calcification. Vascular damage may be involved in the development of brain …

Osteoglycin, a fundamental proteoglycan within the vascular extracellular matrix, is
expressed in vascular smooth muscle cells (VSMCs). Type 2 diabetes (T2D) is associated …

Background: Vascular calcification, causing cardiovascular morbidity and mortality, is
associated with hyperphosphatemia in chronic kidney disease (CKD). In vitro, phosphate …

Plasma factor XIII (pFXIII) is a heterotetramer of FXIII-A and FXIII-B subunits. The cellular
form (cFXIII), a dimer of FXIII-A, is present in a number of cell types. Activated FXIII (FXIIIa), a …

A halálozási statisztikákat világszerte az érelmeszesedés talaján kialakuló kardiovaszkuláris
események (agyvérzés, szívinfarktus) vezetik. Az ateroszklerózis egy lassú, progresszív …

Background: Previous studies reached inconsistent conclusions about the relationship
between alcohol or cigarette consumption and coronary artery calcification (CAC). We aim to …