Proliferative vitreoretinopathy: a review

S Idrees, J Sridhar, AE Kuriyan - International ophthalmology …, 2019 - journals.lww.com
Proliferative vitreoretinopathy (PVR) is the most common cause for failure of
rhegmatogenous retinal detachment repair and is characterized by the growth and …

Proliferative vitreoretinopathy: a new concept of disease pathogenesis and practical consequences

JC Pastor, J Rojas, S Pastor-Idoate, S Di Lauro… - Progress in retinal and …, 2016 - Elsevier
During the last four decades, proliferative vitreoretinopathy (PVR) has defied the efforts of
many researchers to prevent its occurrence or development. Thus, PVR is still the major …

Is neutralizing vitreal growth factors a viable strategy to prevent proliferative vitreoretinopathy?

S Pennock, LJ Haddock, D Eliott, S Mukai… - Progress in retinal and …, 2014 - Elsevier
Proliferative vitreoretinopathy (PVR) is a blinding disorder that occurs in eyes with
rhegmatogenous retinal detachment and in eyes that have recently undergone retinal …

Inflammatory mediators of proliferative vitreoretinopathy: hypothesis and review

Y Dai, C Dai, T Sun - International ophthalmology, 2020 - Springer
Purpose To review the role of inflammatory mediators in proliferative vitreoretinopathy (PVR)
development and the current treatment for PVR prevention. Methods A PubMed search was …

Ageing of the vitreous: from acute onset floaters and flashes to retinal detachment

X Lumi, M Hawlina, D Glavač, A Facskó, MC Moe… - Ageing Research …, 2015 - Elsevier
Floaters and flashes are most commonly symptoms of age-related degenerative changes in
the vitreous body and posterior vitreous detachment. The etiology and pathogenesis of …

Transfer learning for genotype–phenotype prediction using deep learning models

M Muneeb, S Feng, A Henschel - BMC bioinformatics, 2022 - Springer
Background For some understudied populations, genotype data is minimal for genotype-
phenotype prediction. However, we can use the data of some other large populations to …

Targeting Keap1 by miR-626 protects retinal pigment epithelium cells from oxidative injury by activating Nrf2 signaling

X Xu, Y Tang, L Cheng, J Yao, Q Jiang, K Li… - Free Radical Biology and …, 2019 - Elsevier
Activation of the NF-E2-related factor 2 (Nrf2) cascade can offer significant protection against
oxidative stress in retinal pigment epithelium (RPE) cells. Here, we identified a novel kelch …

Proliferative vitreoretinopathy: a reappraisal

P Carpineto, AM Licata, M Ciancaglini - Journal of Clinical Medicine, 2023 - mdpi.com
Proliferative vitreoretinopathy (PVR) remains the main cause of failure after retinal
detachment (RD) surgery. Despite the development of modern technologies and …

Personalized proteomics in proliferative vitreoretinopathy implicate hematopoietic cell recruitment and mTOR as a therapeutic target

CN Roybal, G Velez, MA Toral, SH Tsang… - American journal of …, 2018 - Elsevier
Purpose To profile vitreous cytokine expression of proliferative vitreoretinopathy (PVR)
patients. Design Case-control study. Methods Liquid biopsies were collected from 2 groups …

The roles of mouse double minute 2 (MDM2) oncoprotein in ocular diseases: A review

H Jiang, J Luo, H Lei - Experimental Eye Research, 2022 - Elsevier
Abstract Mouse double minute 2 (MDM2), an E3 ubiquitin ligase and the primary negative
regulator of the tumor suppressor p53, cooperates with its structural homolog MDM4/MDMX …