Hyperpolarised gas lung MRI using xenon-129 can provide detailed 3D images of the
ventilated lung airspaces, and can be applied to quantify lung microstructure and detailed …

This review focuses on the state‐of‐the‐art of the three major classes of gas contrast agents
used in magnetic resonance imaging (MRI)—hyperpolarized (HP) gas, molecular oxygen …

Hyperpolarized (HP) 129Xe MRI uniquely images pulmonary ventilation, gas exchange, and
terminal airway morphology rapidly and safely, providing novel information not possible …

Purpose To quantitatively compare hyperpolarized helium 3 (3He) and xenon 129 (129Xe)
magnetic resonance (MR) images obtained within 5 minutes in healthy volunteers and …

Background Patients with eosinophilic asthma often report poor symptomatic control and
quality of life. Anti-IL-5 therapy, including anti-IL-5Rα (benralizumab), rapidly depletes …

Purpose To compare hyperpolarized helium‐3 (3He) and xenon‐129 (129Xe) MRI in
asthmatics before and after salbutamol inhalation. Materials and Methods Seven asthmatics …

Methods We completed a single-center, randomized, double-blind, placebo-controlled trial
(ClinicalTrials. gov identifier NCT 03884842) in 25 adults with uncontrolled moderate to …

Background Intraluminal contributor (s) to airflow obstruction in severe asthma are patient-
specific and must be evaluated to personalize treatment. The occurrence and functional …

Background Patients often report persistent symptoms beyond the acute infectious phase of
COVID-19. Hyperpolarised 129Xe MRI provides a way to directly measure airway functional …

Purpose To quantify regional lung ventilation in healthy volunteers and patients with severe
asthma (both before and after thermoplasty) by using a combination of helium 3 (3He) …