Current insights on antifungal therapy: Novel nanotechnology approaches for drug delivery systems and new drugs from natural sources

F Sousa, D Ferreira, S Reis, P Costa - Pharmaceuticals, 2020 - mdpi.com
The high incidence of fungal infections has become a worrisome public health issue, having
been aggravated by an increase in host predisposition factors. Despite all the drugs …

Synergistic combination of antioxidants, silver nanoparticles and chitosan in a nanoparticle based formulation: Characterization and cytotoxic effect on MCF-7 breast …

D Nayak, AP Minz, S Ashe, PR Rauta, M Kumari… - Journal of colloid and …, 2016 - Elsevier
Abstract Hypothesis Chitosan (Cs) is a biocompatible, biodegradable cationic polymer
having the ability of targeted drug delivery. Vitamin E and C are not synthesized in our body …

Stavudine loaded gelatin liposomes for HIV therapy: Preparation, characterization and in vitro cytotoxic evaluation

D Nayak, A Boxi, S Ashe, NC Thathapudi… - Materials Science and …, 2017 - Elsevier
Despite continuous research and availability of 25 different active compounds for treating
chronic HIV-1 infection, there is no absolute cure for this deadly disease. Primarily, the …

Ketoconazole and Ketoconazole/β-cyclodextrin performance on cotton wound dressing as fungal skin treatment

N Hedayati, M Montazer, M Mahmoudirad… - Carbohydrate polymers, 2020 - Elsevier
Here, a cotton wound dressing was prepared with control release of Ketoconazole (KZ) to
kill skin fungus. KZ alone and KZ/β-cyclodextrin (β-CD) were loaded on cotton through …

Bioengineered ethosomes encapsulating AgNPs and Tasar silk sericin proteins for non melanoma skin carcinoma (NMSC) as an alternative therapeutics

D Nayak, NC Thathapudi, S Ashe, B Nayak - International Journal of …, 2021 - Elsevier
Rising cases of Non melanoma skin carcinoma (NMSC) and escalating levels of ultraviolet
radiations have underlined a profound correlation with the elevating levels of environmental …

Ketoconazole-loaded PLGA nanoparticles and their synergism against Candida albicans when combined with silver nanoparticles

SK Sadozai, SA Khan, N Karim, D Becker… - Journal of Drug Delivery …, 2020 - Elsevier
Ketoconazole is one of the most commonly used azole drug applied in the treatment of
topical fungal infections. However, due to low aqueous solubility, Ketoconazole has limited …

Formulation development and evaluation of fluvastatin loaded transethosomes: Characterization, stability, in vitro dermal penetration, cytotoxicity and antipsoriatic …

AG Yurtsever, A Ekmekcioglu, M Muftuoglu… - Journal of Drug Delivery …, 2024 - Elsevier
Psoriasis, a common immune-mediated chronic inflammatory disease, may arise from
genetic, epigenetic, and immune system factors. Current medications focus on symptom …

Nanotechnology-based Drug Delivery of Topical Antifungal Agents

S Singh, VM Patil, SK Paliwal… - Pharmaceutical …, 2024 - ingentaconnect.com
Among the various prominent fungal infections, superficial ones are widespread. A large
number of antifungal agents and their formulations for topical use are commercially …

Ketoconazole solubility in aqueous binary mixtures of 1‑propanol at various temperatures

A Hatefi, E Rahimpour, F Martinez… - Journal of Molecular …, 2019 - Elsevier
The aim of this work is to have a brief overview on various solubilization methods reported
for ketoconazole and using a commonly used method, ie cosolvency for enhancement of …

[HTML][HTML] 纳米药物递释系统在抗真菌感染治疗中的应用及机制

陈水生, 周可倩, 李晓东, 吕权真, 俞媛 - 药学学报, 2021 - html.rhhz.net
真菌感染对人类健康的威胁呈螺旋式上升, 尤其临床中侵袭性真菌感染影响重症或免疫功能改变
的患者, 感染的发病率和死亡率很高. 药物治疗中, 脱靶毒性以及耐药真菌问题日益严峻 …