Treat-to-target in systemic lupus erythematosus: advancing towards its implementation

AR Parra Sánchez, AE Voskuyl… - Nature reviews …, 2022 - nature.com
The treat-to-target (T2T) concept has improved outcomes for patients with diabetes,
hypertension and rheumatoid arthritis. This therapeutic strategy involves choosing a well …

Synthetic pharmacotherapy for systemic lupus erythematosus: Potential mechanisms of action, efficacy, and safety

AM Téllez Arévalo, A Quaye, LC Rojas-Rodríguez… - Medicina, 2022 - mdpi.com
The pharmacological treatment of systemic lupus erythematosus (SLE) aims to decrease
disease activity, progression, systemic compromise, and mortality. Among the …

Dysregulation of innate and adaptive serum mediators precedes systemic lupus erythematosus classification and improves prognostic accuracy of autoantibodies

R Lu, ME Munroe, JM Guthridge, KM Bean, DA Fife… - Journal of …, 2016 - Elsevier
Systemic lupus erythematosus (SLE) is a complex autoimmune disease with a poorly
understood preclinical stage of immune dysregulation and symptom accrual. Accumulation …

miR‑101‑3p negatively regulates inflammation in systemic lupus erythematosus via MAPK1 targeting and inhibition of the NF‑κB pathway

X Zhao, S Li, Z Wang, N Bai… - Molecular Medicine …, 2021 - spandidos-publications.com
Systemic lupus erythematosus (SLE) is an autoimmune disease often used as a model in
genomics research. The downregulation of microRNA‑101‑3p (miR‑101‑3p) participates in …

Impact of antimalarial (AM) on serum lipids in systemic lupus erythematosus (SLE) patients: a systematic review and meta-analysis

CY Tao, J Shang, T Chen, D Yu, YM Jiang, D Liu… - Medicine, 2019 - journals.lww.com
Background: Dyslipidemia is a common disorder in systemic lupus erythematosus (SLE)
patients. It is still inconclusive whether antimalarial drugs could affect the serum lipids in SLE …

Clinical characterization of a cohort of patients treated for systemic lupus erythematosus in Colombia: A retrospective study

JE Machado-Alba, ME Machado-Duque… - Plos one, 2023 - journals.plos.org
Introduction Systemic lupus erythematosus is an autoimmune disease associated with
serious complications and high costs. The aim was to describe the clinical characteristics …

The soluble cytoplasmic tail of CD45 (ct‐CD45) in human plasma contributes to keep T cells in a quiescent state

A Puck, S Hopf, M Modak, O Majdic… - European journal of …, 2017 - Wiley Online Library
The cytoplasmic tail of CD45 (ct‐CD45) is proteolytically cleaved and released upon
activation of human phagocytes. It acts on T cells as an inhibitory, cytokine‐like factor in …

[HTML][HTML] Pulmonary protective effects of ultrasonic green synthesis of gold nanoparticles mediated by pectin on Methotrexate-induced acute lung injury in lung BEAS …

D Wang, J Pu, Y Liao, J Liu, G Hu - Arabian Journal of Chemistry, 2022 - Elsevier
Regarding applicative, facile, green chemical research, a bio-inspired approach is being
reported for the synthesis of Au nanoparticles by pectin (PEC) as a natural reducing and …

Progressive multifocal leukoencephalopathy and systemic lupus erythematosus: focus on etiology

S Ghaderi Berntsson, E Katsarogiannis… - Case Reports in …, 2016 - karger.com
Progressive multifocal leukoencephalopathy (PML) caused by reactivation of the JC virus
(JCV), a human polyomavirus, occurs in autoimmune disorders, most frequently in systemic …

Cyclophosphamide-induced severe acute hepatitis in a rheumatic disease: case-based review

D Üsküdar Cansu, E Öztaş, E Yilmaz… - Rheumatology …, 2019 - Springer
In rheumatology practice, the risk of hepatotoxicity from medications, including non-steroidal
anti-inflammatory drugs, notably, and methotrexate, sulfasalazine, leflunomide, and …