Neurological and metabolic related pathophysiologies and treatment of comorbid diabetes with depression

S Li, D Yang, X Zhou, L Chen, L Liu… - CNS Neuroscience …, 2024 - Wiley Online Library
Background The comorbidity between diabetes mellitus and depression was revealed, and
diabetes mellitus increased the prevalence of depressive disorder, which ranked 13th in the …

Clozapine safety monitoring and related research in psychiatry and neurology in South America: A scoping review

T Baptista, A Serrano, APL Presti… - Schizophrenia …, 2024 - Elsevier
The quality and quantity of clozapine safety monitoring considerably differs among South
American countries and mainly focus on hematological surveillance. Few studies have been …

Clozapine and its protective effect on all-cause, natural, and suicide mortality in patients with schizophrenia: a nationwide cohort study in Taiwan

WY Chen, PH Chen, CH Pan, SS Su, SY Tsai… - Schizophrenia …, 2024 - Elsevier
Aim Clozapine is indicated as the last-line agent for the treatment of refractory schizophrenia
due to its side effects. This study included an Asian schizophrenia population and …

Second to none: rationale, timing, and clinical management of clozapine use in schizophrenia

M Qubad, RA Bittner - Therapeutic Advances in …, 2023 - journals.sagepub.com
Despite its enduring relevance as the single most effective and important evidence-based
treatment for schizophrenia, underutilization of clozapine remains considerable. To a …

The relationship of cardiovascular disease risk, clozapine antipsychotic use and cognitive function in a large Chinese schizophrenia cohort

C Lu, X Jin, N Liu, Y Li, Y Dong, X Wang, S Li, J Li - Brain Research, 2024 - Elsevier
Objective This study explores the intricate relationship between clozapine use,
cardiovascular disease (CVD) risk, and cognitive function in patients with schizophrenia …

An expert review of clozapine in Latin American countries: Use, monitoring, and pharmacovigilance

T Baptista, M Motuca, A Serrano, APL Presti… - Schizophrenia …, 2023 - Elsevier
There is growing interest in clozapine clinical use, monitoring, and research, particularly
adverse drug reactions (ADRs) other than agranulocytosis. In this study we focused on …

Lurasidone blocks the voltage-gated potassium channels of coronary arterial smooth muscle cells

W Zhuang, SY Mun, M Park, J Jeong, H Park… - European Journal of …, 2023 - Elsevier
Lurasidone is a second-generation antipsychotic drug used to treat schizophrenia, mania,
and bipolar disorder. The drug is an antagonist of the 5-HT 2A and D 2 receptors. No effect …

Influence of antipsychotic medications on hyperlipidemia risk in patients with schizophrenia: evidence from a population-based cohort study and in vitro hepatic lipid …

TY Wu, N Tien, CL Lin, YC Cheah, CY Hsu… - Frontiers in …, 2023 - frontiersin.org
Introduction Schizophrenia increases the risk of mortality and cardiovascular disease (CVD)
risk. However, the correlation between antipsychotics (APs) and CVD remains controversial …