Bone cells, namely osteoblasts and osteoclasts work in concert and are responsible for
bone extracellular matrix formation and resorption. This homeostasis is, in part, altered …

Bacteria such as Staphylococcus aureus are successful as commensal organisms or
pathogens in part because they adapt rapidly to selective pressures imparted by the human …

A wide variety of pathogenic microorganisms have been demonstrated to cause eukaryotic
cell death, either as a consequence of infecting host cells or by producing toxic products …

Staphylococcus aureus uses a plethora of virulence factors to accommodate a diversity of
niches in its human host. Aside from the classical manifestations of S. aureus-induced …

Community Acquired Methicillin Resistant Staphylococcus aureus (CA-MRSA) causes
severe necrotizing infections of the skin, soft tissues, and lungs. Staphylococcal α-hemolysin …

Neutrophils, complement system and skin collectively represent the main elements of the
innate immune system, the first line of defense of the host against many common …

Abstract In this White Paper, we discuss the current state of microbial cancer therapy. This
paper resulted from a meeting ('Microbial Based Cancer Therapy') at the US National …

Organisms from all kingdoms produce pore-forming proteins, with the best-characterized
being of bacterial origin. The last decade of research has revealed that the channels formed …

Staphylococcus aureus is a common bacterial etiology of serious infectious diseases. S.
aureus can invade various types of non-professional phagocytes to produce host cell death …

Staphylococcus aureus is an important pathogen that continues to be a significant global
health threat because of the prevalence of methicillin‐resistant S. aureus strains (MRSA) …