Trauma-and disease-related skeletal defects and illnesses are plaguing millions of people
especially in an ageing globe. Recently, the convergence of additive manufacturing (AM) …

Abstract 3D bioprinting is a pioneering technology that enables fabrication of biomimetic,
multiscale, multi-cellular tissues with highly complex tissue microenvironment, intricate …

Recent advances in human pluripotent stem cell (hPSC) differentiation protocols have
generated insulin-producing cells resembling pancreatic β cells. While these stem cell …

Insulin-producing β cells created from human pluripotent stem cells have potential as a
therapy for insulin-dependent diabetes, but human pluripotent stem cell-derived islets (SC …

Abstract Three-dimensional (3D) printing has revolutionized the world manufacturing
production. In biomedical applications, however, 3D printed constructs fell short of …

Diabetes involves the death or dysfunction of pancreatic β-cells. Analysis of bulk sequencing
from human samples and studies using in vitro and in vivo models suggest that endoplasmic …

Differentiation of insulin-producing pancreatic β cells from induced pluripotent stem cells
(iPSCs) derived from patients with diabetes promises to provide autologous cells for …

The field of tissue engineering has advanced over the past decade, but the largest impact on
human health should be achieved with the transition of engineered solid organs to the clinic …

Stem‐cell‐based therapies have the potential to provide novel solutions for the treatment of
a variety of diseases, but the main obstacles to such therapies lie in the uncontrolled …

For the past century, insulin injections have saved millions of lives, but glycemic instability is
still a persistent challenge for people with diabetes, leading to tremendous morbidity and …