Steering the course of CAR T cell therapy with lipid nanoparticles

MB Khawar, A Afzal, Y Si, H Sun - Journal of Nanobiotechnology, 2024 - Springer
Lipid nanoparticles (LNPs) have proven themselves as transformative actors in chimeric
antigen receptor (CAR) T cell therapy, surpassing traditional methods and addressing …

[HTML][HTML] Lipid nanoparticle-mediated messenger RNA delivery for ex vivo engineering of natural killer cells

S Douka, LE Brandenburg, C Casadidio… - Journal of Controlled …, 2023 - Elsevier
Natural killer (NK) cells participate in the immune system by eliminating cancer and virally
infected cells through germline-encoded surface receptors. Their independence from prior …

Polysarcosine-functionalized mRNA lipid nanoparticles tailored for immunotherapy

C Wilhelmy, IS Keil, L Uebbing, MA Schroer, D Franke… - Pharmaceutics, 2023 - mdpi.com
Lipid nanoparticles (LNPs) have gained great attention as carriers for mRNA-based
therapeutics, finding applications in various indications, extending beyond their recent use …

Lipid nanoparticles-based RNA therapies for breast cancer treatment

L Serpico, Y Zhu, RF Maia, S Sumedha… - Drug Delivery and …, 2024 - Springer
Breast cancer (BC) prevails as a major burden on global healthcare, being the most
prevalent form of cancer among women. BC is a complex and heterogeneous disease, and …

The protective role of basal metabolic rate in cognitive decline: evidence from epidemiological and genetic studies

T Meng, C Liu, B Wang, C Li, J Liu… - Postgraduate …, 2024 - academic.oup.com
Purpose This study aims to explore the relationship between basal metabolic rate (BMR)
and cognitive impairment and assess the potential of BMR as a protective factor against …

Microfluidics: Current and Future Perspectives

JM Wagaman, E Weaver… - … , Drug Delivery, Screening …, 2024 - books.google.com
The advancement of microfluidics (MFs) for use in a variety of fields has pushed forward
technology in many areas, including rapid diagnostics, point-ofcare devices, therapeutic …

[PDF][PDF] mRNA vaccines A bridge between preventive and therapeutic medicine

A Rapp - researchgate.net
In mRNA technology, prevention and therapy merge into a uniform medical strategy. In
preventive applications, mRNA acts as a molecular guide to stimulate the body's cells to …