Ebola virus (EBOV) is one of the lethal viruses, causing more than 24 epidemic outbreaks to
date. Despite having available molecular knowledge of this virus, no definite vaccine or …

The interaction between T-cell receptors (TCRs) and major histocompatibility complex
(MHC)-bound epitopes is one of the most important processes in the adaptive human …

Subolesin/akirin is a protective antigen that is highly conserved across hematophagous
vector species and is therefore potentially useful for the development of a universal vaccine …

Presentation of antigenic peptides to T-cell receptors is an essential step in the adaptive
immune response. In the mouse the class Ib major histocompatibility complex molecule, H2 …

Strategies that target multiple components are usually required for treatment of diseases
originating from complex biological systems. The multicomponent system consisting of the …

One key step in the immune response against infected or tumor cells is the recognition of the
T-cell receptor (TCR) by class I major histocompatibility complexes. The complex between …

Computational Immunology: Applications focuses on different mathematical models,
statistical tools, techniques, and computational modelling that helps in understanding …

Computational identification of potential epitopes with an immunogenic capacity challenges
immunological research. Several methods show considerable success, and together with …

The Epstein–Barr virus determinant peptide EENLLDFVRF shows high immunogenicity
when presented by HLA-B* 4405 allotype. This fact is accompanied by a cis–trans …

Human MUC1 is over-expressed in human adenocarcinomas and has been used as a
target for immunotherapy studies. The 9-mer MUC1-9 peptide has been identified as one of …