LGL leukemia: from pathogenesis to treatment
T Lamy, A Moignet… - Blood, The Journal of the …, 2017 - ashpublications.org
Large granular lymphocyte (LGL) leukemia has been recognized by the World Health
Organization classifications amongst mature T-cell and natural killer (NK) cell neoplasms …
Organization classifications amongst mature T-cell and natural killer (NK) cell neoplasms …
[PDF][PDF] Biology and clinical relevance of human natural killer cells
MJ Robertson, J Ritz - 1990 - researchgate.net
ATURAL KILLER (NK) cells comprise 10% to 15% N of human peripheral blood
lymphocytes (PBL) and most have the morphology of large granular lymphocytes (LGL).'s2 …
lymphocytes (PBL) and most have the morphology of large granular lymphocytes (LGL).'s2 …
Clonal diseases of large granular lymphocytes [see comments]
TPJ Loughran - 1993 - ashpublications.org
Three distinct clinical syndromes occur in patients with increased numbers of circulating
LGL. Patients with T-LGL leukemia have clonal proliferations of CD3+ LGL typically …
LGL. Patients with T-LGL leukemia have clonal proliferations of CD3+ LGL typically …
How I treat LGL leukemia
T Lamy, TP Loughran Jr - Blood, The Journal of the American …, 2011 - ashpublications.org
Large granular lymphocyte (LGL) leukemia is characterized by a clonal expansion of either
CD3+ cytotoxic T or CD3− NK cells. Prominent clinical features of T-LGL leukemia include …
CD3+ cytotoxic T or CD3− NK cells. Prominent clinical features of T-LGL leukemia include …
The lymphoproliferative disease of granular lymphocytes: updated criteria for diagnosis
G Semenzato, R Zambello… - Blood, The Journal …, 1997 - ashpublications.org
The lymphoproliferative disease of granular lymphocytes (LDGL), also referred to as LGL
leukemia, is a heterogeneous disorder, but is clinically, morphologically, and …
leukemia, is a heterogeneous disorder, but is clinically, morphologically, and …
[HTML][HTML] Analysis of a French cohort of patients with large granular lymphocyte leukemia: a report on 229 cases
B Bareau, J Rey, M Hamidou, J Donadieu… - …, 2010 - ncbi.nlm.nih.gov
Background Large granular lymphocyte leukemia is a rare lymphoproliferative disorder
associated with autoimmune diseases and impaired hematopoiesis. This study describes …
associated with autoimmune diseases and impaired hematopoiesis. This study describes …
Large granular lymphocyte leukemia
L Sokol, TP Loughran Jr - The oncologist, 2006 - academic.oup.com
Learning Objectives After completing this course, the reader will be able to: Discuss the
basic principles of molecular and cellular biology of LGL leukemia. Describe distinct clinical …
basic principles of molecular and cellular biology of LGL leukemia. Describe distinct clinical …
Clinical spectrum of clonal proliferations of T-large granular lymphocytes: a T-cell clonopathy of undetermined significance?
MV Dhodapkar, CY Li, JA Lust, A Tefferi, RL Phyliky - 1994 - ashpublications.org
We identified 68 patients with clonal T-large granular lymphocyte (T-LGL) proliferations who
were seen at the Mayo Clinic between 1984 and 1992. Nineteen (28%) were asymptomatic …
were seen at the Mayo Clinic between 1984 and 1992. Nineteen (28%) were asymptomatic …
Clinical features of large granular lymphocyte leukemia
T Lamy, TP Loughran Jr - Seminars in hematology, 2003 - Elsevier
The spectrum of large granular lymphocyte (LGL) proliferations consists of four distinct
entities: reactive/transient LGL expansion, chronic LGL lymphocytosis, classical indolent …
entities: reactive/transient LGL expansion, chronic LGL lymphocytosis, classical indolent …
Stat3 mutations impact on overall survival in large granular lymphocyte leukemia: a single-center experience of 205 patients
G Barilà, A Teramo, G Calabretto, C Vicenzetto… - Leukemia, 2020 - nature.com
Large granular lymphocyte leukemia (LGLL) is a rare and chronic lymphoproliferative
disorder characterized by the clonal expansion of LGLs. LGLL patients can be asymptomatic …
disorder characterized by the clonal expansion of LGLs. LGLL patients can be asymptomatic …