Exosomes play a role as mediators of cell-to-cell communication, thus exhibiting pleiotropic
activities to homeostasis regulation. Exosomal non-coding RNAs (ncRNAs), mainly …

Diabetes mellitus (DM) is considered as a main challenge in both developing and
developed countries, as lifestyle has changed and its management seems to be vital. Type I …

Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

Micro-RNAs (miRNAs) are a class of non-coding RNAs (ncRNAs) that act as post-
transcriptional regulators of gene expression. Since their discovery in 1993, they have been …

Wound healing is one of the major global health concerns in patients with diabetes.
Overactivation of pro-inflammatory M1 macrophages is associated with delayed wound …

Nuciferine aporphine alkaloid mainly exists in Nelumbo nucifera Gaertn and is a beneficial
to human health, such as anti-obesity, lowering blood lipid, prevention of diabetes and …

Aims/hypothesis Macrophage levels are elevated in pancreatic islets, and the resulting
inflammatory response is a major contributor to beta cell failure during obesity and type 2 …

Diabetes mellitus (DM) is a chronic systemic disease with increasing prevalence globally.
An important aspect of diabetic pathogenesis is cellular crosstalk and information exchange …

The microRNA-29 family members miR-29a-3p, miR-29b-3p, and miR-29c-3p are
ubiquitously expressed and consistently increased in various tissues and cell types in …

Schisandrin A (SA) is a bioactive lignan isolated from the traditional Chinese medicine
Fructus schisandrae chinensis. In recent years, it has attracted extensive attention because …