A comprehensive account on recent progress in pharmacological activities of benzimidazole derivatives

SR Brishty, MJ Hossain, MU Khandaker… - Frontiers in …, 2021 - frontiersin.org
Nowadays, nitrogenous heterocyclic molecules have attracted a great deal of interest
among medicinal chemists. Among these potential heterocyclic drugs, benzimidazole …

Recent advances in antiviral benzimidazole derivatives: a mini review

A Kanwal, M Ahmad, S Aslam, SAR Naqvi… - Pharmaceutical …, 2019 - Springer
Benzimidazole ring system is well known for its potential for various biological activities.
Recent research works have indicated the excellent antiviral potential of various derivatives …

Design, synthesis, mechanistic studies and in silico ADME predictions of benzimidazole derivatives as novel antifungal agents

MM Morcoss, MN El Shimaa, RA Ibrahem… - Bioorganic …, 2020 - Elsevier
Herein, novel three series of benzimidazole scaffold bearing hydrazone, 1, 2, 4-triazole and
1, 3, 4-oxadiazole moieties 1-3, 4a-j, 6a-c and 7 derivatives were designed, synthesized and …

Recent achievements in the synthesis of benzimidazole derivatives

NT Chung, VC Dung, DX Duc - RSC advances, 2023 - pubs.rsc.org
Benzimidazoles are a class of heterocyclic compounds in which a benzene ring is fused to
the 4 and 5 positions of an imidazole ring. Benzimidazole refers to the parent compound …

Antihypertensive effect of a novel angiotensin II receptor blocker fluorophenyl benzimidazole: contribution of cGMP, voltage-dependent calcium channels, and BKCa …

H Iqbal, AK Verma, P Yadav, S Alam… - Frontiers in …, 2021 - frontiersin.org
Background: The current study presents the novel angiotensin II receptor blocker
fluorophenyl benzimidazole (FPD) as an antihypertensive agent in the SHR model of …

[HTML][HTML] A Review on Benzimidazole Heterocyclic Compounds: Synthesis and Their Medicinal Activity Applications

LA Mohammed, MA Farhan, SA Dadoosh… - …, 2023 - thieme-connect.com
Benzimidazole is a heterocyclic compound that contains two nitrogen atoms and is formed
by fusing a benzene ring with an imidazole. Benzimidazole and its derivatives are prepared …

Novel Benzimidazole/Hydrazone Derivatives as Promising Anticancer Lead Compounds: Design, Synthesis, and Molecular Docking Study

MM Morcoss, ES Abdelhafez… - Journal of advanced …, 2020 - journals.ekb.eg
A novel series of benzimidazole-hydrazone derivatives was designed and synthesized as a
potential anti-cancer agents. The structure of the target compounds was assured using …

Synthesis, characterization, and investigation of antiproliferative activity of novel Ag (I)-N-Heterocyclic Carbene (NHC) compounds

E Çevik-Yıldız, N Şahin, S Şahin-Bölükbaşı - Journal of Molecular Structure, 2020 - Elsevier
The aim of this study was to present the synthesis, characterization, and investigation of the
antiproliferative activity of new metal N-Heterocyclic Carbene (NHC) salts (1a-c) and their Ag …

Benzimidazolium Salts Bearing Nitrile Moieties: Synthesis, Enzyme Inhibition Profiling, and Molecular Docking Analysis for Carbonic Anhydrase and …

E Öner, Y Gök, Y Demir, T Taskin‐Tok… - Chemistry & …, 2023 - Wiley Online Library
This report presents the synthesis and characterization of a range of benzimidazolium salts
featuring 3‐cyanopropyl groups on the 1st nitrogen atom and varied alkyl groups on the 3rd …

The modulated luminescent materials based on benzimidazole and indazole skeletons: Synthesis, crystal structure and Hirshfeld surface analysis

Y Zhou, H Li, YX Ma, SX Cheng, XM Chen… - Journal of Molecular …, 2024 - Elsevier
To exploit new luminescent materials, three new compounds containing benzimidazoles
and indazole moieties, namely,[HIZBI]+· BS−· H 2 O (1),[HIZBI]+· MBS−· 2H 2 O (2) and …