[HTML][HTML] How Protein Depletion Balances Thrombosis and Bleeding Risk in the Context of Platelet's Activatory and Negative Signaling

H Montecino-Garrido, A Trostchansky… - International Journal of …, 2024 - mdpi.com
Platelets are small cell fragments that play a crucial role in hemostasis, requiring fast
response times and fine signaling pathway regulation. For this regulation, platelets require a …

A computational investigation of occlusive arterial thrombosis

J Du, AL Fogelson - Biomechanics and Modeling in Mechanobiology, 2024 - Springer
The generation of occlusive thrombi in stenotic arteries involves the rapid deposition of
millions of circulating platelets under high shear flow. The process is mediated by the …

[HTML][HTML] Integrating network pharmacology with microRNA microarray analysis to identify the role of miRNAs in thrombosis treated by the Dahuang Zhechong pill

R Shi, S Gao, H Huang, K Jiang, D Wang - Computers in Biology and …, 2024 - Elsevier
Background: Thrombotic diseases are the leading causes of death worldwide, urging for
improvements in treatment strategies. Dahuang Zhechong pill (DHZCP) is a traditional …

[HTML][HTML] Looping flexible fluoropolymer microcapillary film extends analysis times for vertical microfluidic blood testing

RM Sarıyer, KK Gill, SH Needs, NM Reis, CI Jones… - Sensors, 2024 - mdpi.com
The microfluidic measurement of capillary flow can be used to evaluate the response of
biological samples to stimulation, where distance and velocity are altered. Melt-extruded …

Modelling of the in-stent thrombus formation by dissipative particle dynamics

J Liu, Z Fan, X Ye, Y Zhang, M Liu, X Deng - Journal of Theoretical Biology, 2024 - Elsevier
Background Stent implantation is a highly efficacious intervention for the treatment of
coronary atherosclerosis. Nevertheless, stent thrombosis and other post-operative …

[HTML][HTML] Correlation between ABO blood type and lower extremity deep vein thrombosis in elderly patients following hip fracture

X Cui, R Xia, A Chao - American Journal of Translational Research, 2024 - ncbi.nlm.nih.gov
Objective: To examine the correlation between ABO blood type and the incidence of lower
extremity deep vein thrombosis (LEDVT) in elderly patients after hip fracture surgery, while …

[HTML][HTML] Platelet factor XIII-A regulates platelet function and promotes clot retraction and stability

JL Mitchell, G Little, AP Bye, RS Gaspar… - Research and practice …, 2023 - Elsevier
Abstract Background Factor XIII (FXIII) is an important proenzyme in the hemostatic system.
The plasma-derived enzyme activated FXIII cross-links fibrin fibers within thrombi to increase …