Molecular pathology, oxidative stress, and biomarkers in obstructive sleep apnea

PG Meliante, F Zoccali, F Cascone… - International Journal of …, 2023 - mdpi.com
Obstructive sleep apnea syndrome (OSAS) is characterized by intermittent hypoxia (IH)
during sleep due to recurrent upper airway obstruction. The derived oxidative stress (OS) …

Neurotrophins in the neuropathophysiology, course, and complications of obstructive sleep apnea—a narrative review

A Gabryelska, S Turkiewicz, M Ditmer… - International Journal of …, 2023 - mdpi.com
Obstructive sleep apnea (OSA) is a disorder characterized by chronic intermittent hypoxia
and sleep fragmentation due to recurring airway collapse during sleep. It is highly prevalent …

An exploratory study on the association between serotonin and sleep breathing disorders

M Wieckiewicz, H Martynowicz, G Lavigne… - Scientific Reports, 2023 - nature.com
This exploratory observational study aimed to evaluate whether the blood levels of serotonin
and enzymes involved in serotonin synthesis are associated with sleep breathing …

The role of microRNAs in pathophysiology and diagnostics of metabolic complications in obstructive sleep apnea patients

FF Karuga, J Jaromirska, M Malicki… - Frontiers in Molecular …, 2023 - frontiersin.org
Obstructive sleep apnea (OSA) is one of the most common sleep disorders, which is
characterized by recurrent apneas and/or hypopneas occurring during sleep due to upper …

Influence of glutamatergic and GABAergic neurotransmission on obstructive sleep apnea

P Kaczmarski, M Sochal, D Strzelecki… - Frontiers in …, 2023 - frontiersin.org
Glutamate and γ-aminobutyric acid (GABA) are the two main neurotransmitters in the human
brain. The balance between their excitatory and inhibitory functions is crucial for maintaining …

Relation between selected sleep parameters, depression, anti-tumor necrosis factor therapy, and the brain-derived neurotrophic factor pathway in inflammatory bowel …

M Sochal, M Ditmer, A Binienda, A Gabryelska… - Metabolites, 2023 - mdpi.com
Inflammatory bowel disease (IBD) patients often have sleep and mood disorders. Brain-
derived neurotrophic factor (BDNF) and proBDNF were shown to modulate interactions …

Investigating the Role of BDNF in Insomnia: Current Insights

M Ditmer, A Gabryelska, S Turkiewicz… - Nature and Science of …, 2023 - Taylor & Francis
Insomnia is a common disorder defined as frequent and persistent difficulty initiating,
maintaining, or going back to sleep. A hallmark symptom of this condition is a sense of …

A systematic review with meta-analysis to assess Alzheimer's disease biomarkers in adults with or without obstructive sleep apnoea

I Mohammadi, M Adibparsa, A Najafi, MS Sehat… - International …, 2023 - Elsevier
Introduction The aim was to design a meta-analysis evaluating the positron emission
tomography (PET) uptake and cerebrospinal fluid (CSF), circulating levels of amyloid-β (Aβ) …

Shedding light on neurofilament involvement in cognitive decline in obstructive sleep apnea and its possible role as a biomarker

J Jaromirska, P Kaczmarski, D Strzelecki… - Frontiers in …, 2023 - frontiersin.org
Obstructive sleep apnea is one of the most common sleep disorders with a high estimated
global prevalence and a large number of associated comorbidities in general as well as …

Evaluation of daytime sleepiness and insomnia symptoms in OSA patients with a characterization of symptom-defined phenotypes and their involvement in depression …

A Gabryelska, S Turkiewicz, P Białasiewicz… - Frontiers in …, 2024 - frontiersin.org
Introduction Recent research highlights the significance of insomnia and sleepiness, shifting
from obstructive sleep apnea (OSA) severity and sleep structure, in defining OSA …