Chordoma is a rare, but often malignant, bone cancer that preferentially affects the axial
skeleton and the skull base. These tumors are both sporadic and hereditary and appear to …

266 Curcumin-Loaded γ-Cyclodextrin Liposomal Nanoparticles as Delivery Vehicles
received significant attention because of its low nonspecific toxicity to normal cells …

Purposes To review in the literature, all the epidemiological, clinical, radiological,
histological and therapeutic data regarding chordomas as well as various notochordal …

Object Chordoma is a malignant bone neoplasm hypothesized to arise from notochordal
remnants along the length of the neuraxis. Recent genomic investigation of chordomas has …

PURPOSE: The provirus integration site for Moloney murine leukemia virus 1 (Pim-1) kinase
is overexpressed in various tumors and has been linked to poor prognosis. Its role as proto …

Simple Summary Chordomas are rare bone tumors characterized by a high recurrence rate.
Presently, no medical treatment is available for advanced diseases due to the lack of …

Chordomas are malignant bone tumors that arise from remnants of the notochord. These
tumors are generally slow-growing, locally aggressive, and invasive. Chordomas are …

Extra‐axial chordoma is a rare neoplasm of extra‐axial skeleton and soft tissue that shares
identical histomorphologic and immunophenotypic features with midline chordoma. While …

Chordoma is a rare primary malignant bone tumor and there exist only a few established
human chordoma cell lines. The scarcity of robust chordoma cell lines has limited the ability …

Skull base chordomas are challenging tumors due to their deep surgical location and
resistance to conventional radiotherapy. Chemotherapy plays a marginal role in the …