Current recommendations and recent progress in endometrial cancer
RA Brooks, GF Fleming, RR Lastra… - CA: a cancer journal …, 2019 - Wiley Online Library
Endometrial cancer is the most common gynecologic cancer in the United States, and its
incidence is rising. Although there have been significant recent advances in our …
incidence is rising. Although there have been significant recent advances in our …
Clinical actionability of molecular targets in endometrial cancer
ME Urick, DW Bell - Nature Reviews Cancer, 2019 - nature.com
Abstract Endometrial cancer accounts for~ 76,000 deaths among women each year
worldwide. Disease mortality and the increasing number of new diagnoses make …
worldwide. Disease mortality and the increasing number of new diagnoses make …
[HTML][HTML] Integrated analysis of TP53 gene and pathway alterations in the cancer genome atlas
The TP53 tumor suppressor gene is frequently mutated in human cancers. An analysis of
five data platforms in 10,225 patient samples from 32 cancers reported by The Cancer …
five data platforms in 10,225 patient samples from 32 cancers reported by The Cancer …
Patient-derived organoids from endometrial disease capture clinical heterogeneity and are amenable to drug screening
M Boretto, N Maenhoudt, X Luo, A Hennes… - Nature cell …, 2019 - nature.com
Endometrial disorders represent a major gynaecological burden. Current research models
fail to recapitulate the nature and heterogeneity of these diseases, thereby hampering …
fail to recapitulate the nature and heterogeneity of these diseases, thereby hampering …
[HTML][HTML] A clinically applicable molecular-based classification for endometrial cancers
A Talhouk, MK McConechy, S Leung… - British journal of …, 2015 - nature.com
Background: Classification of endometrial carcinomas (ECs) by morphologic features is
inconsistent, and yields limited prognostic and predictive information. A new system for …
inconsistent, and yields limited prognostic and predictive information. A new system for …
[HTML][HTML] Integrated genomic characterization of endometrial carcinoma
DA Levine… - Nature, 2013 - nature.com
We performed an integrated genomic, transcriptomic and proteomic characterization of 373
endometrial carcinomas using array-and sequencing-based technologies. Uterine serous …
endometrial carcinomas using array-and sequencing-based technologies. Uterine serous …
New concepts for an old problem: the diagnosis of endometrial hyperplasia
PA Sanderson, HOD Critchley… - Human reproduction …, 2017 - academic.oup.com
BACKGROUND Endometrial hyperplasia (EH) is a uterine pathology representing a
spectrum of morphological endometrial alterations. It is predominantly characterized by an …
spectrum of morphological endometrial alterations. It is predominantly characterized by an …
[HTML][HTML] Integrated molecular characterization of uterine carcinosarcoma
We performed genomic, epigenomic, transcriptomic, and proteomic characterizations of
uterine carcinosarcomas (UCSs). Cohort samples had extensive copy-number alterations …
uterine carcinosarcomas (UCSs). Cohort samples had extensive copy-number alterations …
Classification of endometrial carcinoma: more than two types
R Murali, RA Soslow, B Weigelt - The Lancet Oncology, 2014 - thelancet.com
Endometrial cancer is the most common gynaecological malignancy in Europe and North
America. Traditional classification of endometrial carcinoma is based either on clinical and …
America. Traditional classification of endometrial carcinoma is based either on clinical and …
Endometrial carcinoma: molecular subtypes, precursors and the role of pathology in early diagnosis
Endometrial carcinoma (EC) is classified into a wide range of morphological variants; this list
has expanded over the past decade with the inclusion of mesonephric‐like and …
has expanded over the past decade with the inclusion of mesonephric‐like and …