Recent advances in Brucella abortus vaccines

EMS Dorneles, N Sriranganathan, AP Lage - Veterinary research, 2015 - Springer
Brucella abortus vaccines play a central role in bovine brucellosis control/eradication
programs and have been successfully used worldwide for decades. Strain 19 and RB51 are …

Towards a Brucella vaccine for humans

SD Perkins, SJ Smither, HS Atkins - FEMS microbiology reviews, 2010 - academic.oup.com
There is currently no licensed vaccine for brucellosis in humans. Available animal vaccines
may cause disease and are considered unsuitable for use in humans. However, the …

Production and Targeting of the Brucella abortus Antigen L7/L12 in Lactococcus lactis: a First Step towards Food-Grade Live Vaccines against Brucellosis

LA Ribeiro, V Azevedo, Y Le Loir… - Applied and …, 2002 - Am Soc Microbiol
Brucella abortus is a facultative intracellular gram-negative bacterial pathogen that infects
humans and animals by entry mainly through the digestive tract. B. abortus causes abortion …

Brucella: a pathogen without classic virulence genes

MN Seleem, SM Boyle, N Sriranganathan - Veterinary microbiology, 2008 - Elsevier
The first species of Brucella was isolated and characterized almost 120 years ago and
recently the complete nucleotide sequences of the genomes of a number of well …

Identification of Major Outer Surface Proteins of Streptococcus agalactiae

MJG Hughes, JC Moore, JD Lane, R Wilson… - Infection and …, 2002 - Am Soc Microbiol
To identify the major outer surface proteins of Streptococcus agalactiae (group B
streptococcus), a proteomic analysis was undertaken. An extract of the outer surface …

Protection of BALB/c Mice against Brucella abortus 544 Challenge by Vaccination with Bacterioferritin or P39 Recombinant Proteins with CpG Oligodeoxynucleotides …

A Al-Mariri, A Tibor, P Mertens, X De Bolle… - Infection and …, 2001 - Am Soc Microbiol
The P39 and the bacterioferrin (BFR) antigens of Brucella melitensis 16M were previously
identified as T dominant antigens able to induce both delayed-type hypersensivity in …

Proteomic analysis of Brucella abortus cell envelope and identification of immunogenic candidate proteins for vaccine development

JP Connolly, D Comerci, TG Alefantis, A Walz… - …, 2006 - Wiley Online Library
Brucella abortus is the etiologic agent of bovine brucellosis and causes a chronic disease in
humans known as undulant fever. In livestock the disease is characterized by abortion and …

A DNA Vaccine Encoding Cu,Zn Superoxide Dismutase of Brucella abortus Induces Protective Immunity in BALB/c Mice

AA Onate, S Cespedes, A Cabrera, R Rivers… - Infection and …, 2003 - Am Soc Microbiol
This study was conducted to evaluate the immunogenicity and protective efficacy of a DNA
vaccine encoding Brucella abortus Cu, Zn superoxide dismutase (SOD). Intramuscular …

Characterization of DegQVh, a Serine Protease and a Protective Immunogen from a Pathogenic Vibrio harveyi Strain

W Zhang, K Sun, S Cheng, L Sun - Applied and environmental …, 2008 - Am Soc Microbiol
Vibrio harveyi is an important marine pathogen that can infect a number of aquaculture
species. V. harveyi degQ (degQVh), the gene encoding a DegQ homologue, was cloned …

Differential Proteomic Analysis of the Bacillus anthracis Secretome: Distinct Plasmid and Chromosome CO2-Dependent Cross Talk Mechanisms Modulate …

T Chitlaru, O Gat, Y Gozlan, N Ariel… - Journal of …, 2006 - Am Soc Microbiol
The secretomes of a virulent Bacillus anthracis strain and of avirulent strains (cured of the
virulence plasmids pXO1 and pXO2), cultured in rich and minimal media, were studied by a …