Every individual experiences stressful life events. In some cases acute or chronic stress
leads to depression and other psychiatric disorders, but most people are resilient to such …

Given the high prevalence and burden of mental disorders, fostering the understanding of
protective factors is an urgent issue for translational medicine in psychiatry. The concept of …

Video game playing is a frequent recreational activity. Previous studies have reported an
involvement of dopamine-related ventral striatum. However, structural brain correlates of …

Rationale A dimensional approach in psychiatry aims to identify core mechanisms of mental
disorders across nosological boundaries. Objectives We compared anticipation of reward …

As a step toward addressing limitations in the current psychiatric diagnostic system, the
National Institute of Mental Health recently developed the Research Domain Criteria (RDoC) …

Major Depressive Disorder (MDD) involves deficits in the reward system. While
neuroimaging studies have focused on affective stimulus processing, few investigations …

Identifying patients who are potential placebo responders has major implications for clinical
practice and trial design. Catechol-O-methyltransferase (COMT), an important enzyme in …

Research integrating neuroimaging and molecular genetics has yielded important insights
into how variability in brain chemistry predicts individual differences in brain function …

It is still debated how altruistic punishment as one form of strong reciprocity has established
during evolution and which motives may underlie such behavior. Recent neuroscientific …

Recent research showed that cognitive emotion regulation (ER) both increases activity in the
dorsolateral prefrontal cortex (DLPFC) and decreases striatal responsivity to monetary …