Curcumin induces ferroptosis in follicular thyroid cancer by upregulating HO‐1 expression

H Chen, Z Li, J Xu, N Zhang, J Chen… - Oxidative Medicine …, 2023 - Wiley Online Library
Follicular thyroid cancer (FTC) is a highly aggressive type of endocrine malignancy. It is
necessary to investigate the mechanisms of tumorigenesis and therapeutic pathways in …

Paving the path toward multi-omics approaches in the diagnostic challenges faced in thyroid pathology

I Piga, V L'Imperio, G Capitoli, V Denti… - Expert Review of …, 2023 - Taylor & Francis
Introduction Despite advancements in diagnostic methods, the classification of
indeterminate thyroid nodules still poses diagnostic challenges not only in pre-surgical …

Multi-omics and management of follicular carcinoma of the thyroid

TE Luvhengo, I Bombil, A Mokhtari, MS Moeng… - Biomedicines, 2023 - mdpi.com
Follicular thyroid carcinoma (FTC) is the second most common cancer of the thyroid gland,
accounting for up to 20% of all primary malignant tumors in iodine-replete areas. The …

Artificial intelligence defines protein-based classification of thyroid nodules

Y Sun, S Selvarajan, Z Zang, W Liu, Y Zhu, H Zhang… - Cell discovery, 2022 - nature.com
Determination of malignancy in thyroid nodules remains a major diagnostic challenge. Here
we report the feasibility and clinical utility of developing an AI-defined protein-based …

Risk stratification of papillary thyroid cancers using multidimensional machine learning

Y Li, F Wu, W Ge, Y Zhang, Y Hu, L Zhao… - … Journal of Surgery, 2024 - journals.lww.com
Background: Papillary thyroid cancer (PTC) is one of the most common endocrine
malignancies with different risk levels. However, preoperative risk assessment of PTC is still …

Proteomics profile in encapsulated follicular patterned thyroid neoplasms

TPX Nguyen, S Roytrakul, S Buranapraditkun… - Scientific Reports, 2024 - nature.com
Diagnosing encapsulated follicular-patterned thyroid tumors like Invasive Encapsulated
Follicular Variant of Papillary Thyroid Carcinoma (IEFVPTC), Non-invasive Follicular Thyroid …

The plasma DIA-based quantitative proteomics reveals the pathogenic pathways and new biomarkers in cervical cancer and high grade squamous intraepithelial …

S Han, J Zhang, Y Sun, L Liu, L Guo, C Zhao… - Journal of clinical …, 2022 - mdpi.com
Objective: The process of normal cervix changing into high grade squamous intraepithelial
lesion (HSIL) and invasive cervical cancer is long and the mechanisms are still not …

[HTML][HTML] Automated diagnosis and management of follicular thyroid nodules based on the devised small-dataset interpretable foreground optimization network deep …

Z Yang, S Yao, Y Heng, P Shen, T Lv… - … Journal of Surgery, 2023 - journals.lww.com
Background: Currently, follicular thyroid carcinoma (FTC) has a relatively low incidence with
a lack of effective preoperative diagnostic means. To reduce the need for invasive diagnostic …

Resistance prediction in high‐grade serous ovarian carcinoma with neoadjuvant chemotherapy using data‐independent acquisition proteomics and an ovary‐specific …

L Qian, J Zhu, Z Xue, T Gong, N Xiang… - Molecular …, 2023 - Wiley Online Library
High‐grade serous ovarian carcinoma (HGSOC) is the most common subtype of ovarian
cancer with 5‐year survival rates below 40%. Neoadjuvant chemotherapy (NACT) followed …

[HTML][HTML] 高效液相色谱-质谱技术在蛋白质组学中的应用

LIU Wei, W Lingxiao, GAO Mingxia… - Chinese Journal of …, 2024 - ncbi.nlm.nih.gov
蛋白质组学研究在生物医学领域发挥了重要作用, 然而研究面临的主要难点在于其研究对象的
复杂性和多样性。 随着质谱技术的快速发展, 高效液相色谱-质谱(HPLC-MS) …