Novel approaches concerning the numerical modeling of particle and cell separation in microchannels: A review

IH Karampelas, J Gómez-Pastora - Processes, 2022 - mdpi.com
The demand for precise separation of particles, cells, and other biological matter has
significantly increased in recent years, leading to heightened scientific interest in this topic …

New generation dielectrophoretic-based microfluidic device for multi-type cell separation

P Sharbati, AK Sadaghiani, A Koşar - Biosensors, 2023 - mdpi.com
This study introduces a new generation of dielectrophoretic-based microfluidic device for the
precise separation of multiple particle/cell types. The device features two sets of 3D …

Dielectrophoretic separation and purification: from colloid and biological particles to droplets

S Hu, Y Wang, Y Wang, X Chen, R Tong - Journal of Chromatography A, 2024 - Elsevier
It is indispensable to realize the high level of purification and separation, so that objective
particles, such as malignant cells, harmful bacteria, and special proteins or biological …

Design and analysis of a microfluidic lab-on-chip utilizing dielectrophoresis mechanism for medical diagnosis and liquid biopsy

W Pakhira, R Kumar, KM Ibrahimi… - Journal of the Brazilian …, 2022 - Springer
In the recent years, microfluidic lab-on-chip devices have become very popular in point-of-
care medical diagnosis and liquid biopsy analyses. However, the developed devices are …

Particle separation based on dielectrophoresis force using boundary element method and point-particle approach in a microfluidic channel

M Olfat, E Kadivar - Microfluidics and Nanofluidics, 2023 - Springer
Active sorting of particle in the dielectrophoresis microfluidic channel by applying the
boundary element method and point-particle approach is investigated. In this paper, we …

Numerical investigation of ternary particle separation in a microchannel with a wall-mounted obstacle using dielectrophoresis

R Derakhshan, A Bozorgzadeh, A Ramiar - Journal of Chromatography A, 2023 - Elsevier
In recent years, microfluidic-based particle/cell manipulation techniques have catalyzed
significant advances in several fields of science. As an efficient, precise, and label-free …

Numerical simulation-based performance improvement of the separation of circulating tumor cells from bloodstream in a microfluidic platform by dielectrophoresis

NV Nguyen, H Van Manh, N Van Hieu - Korea-Australia Rheology Journal, 2022 - Springer
Circulating tumor cells (CTCs) detection has become one of the promising solutions for the
early diagnosis of cancers. Thus, the separation of CTCs is of great importance in …

Design and Application of Microfluidic Capture Device for Physical–Magnetic Isolation of MCF-7 Circulating Tumor Cells

A Bendre, D Somasekhara, VK Nadumane, G Sriram… - Biosensors, 2024 - mdpi.com
Circulating tumor cells (CTCs) are a type of cancer cell that spreads from the main tumor to
the bloodstream, and they are often the most important among the various entities that can …

Dielectrophoretic Movement of Cell Passing Between Surface Electrodes in Flow Channel

S Hashimoto, R Ono - Journal of Engineering and …, 2024 - asmedigitalcollection.asme.org
In this study, cell behavior in a microchannel was tracked for the application of
dielectrophoresis to biological cell sorting. A pair of titanium surface electrodes was …

Model-Based Investigation of a Dielectrophoretic Microfluidic Device for the Separation of Polystyrene Particles

W Han, H Zou, Y Zheng, Y Liu, X Wang, W Li… - … Science and Technology, 2024 - Springer
Particle separation holds great significance as it has the potential to enhance product
quality, efficiency, and safety across various industries by selectively sorting particles based …