The melanin-concentrating hormone as an integrative peptide driving motivated behaviors

GB Diniz, JC Bittencourt - Frontiers in systems neuroscience, 2017 - frontiersin.org
The melanin-concentrating hormone (MCH) is an important peptide implicated in the control
of motivated behaviors. History, however, made this peptide first known for its participation in …

Oxytocin facilitates adaptive fear and attenuates anxiety responses in animal models and human studies—potential interaction with the corticotropin-releasing factor …

M Janeček, J Dabrowska - Cell and tissue research, 2019 - Springer
Despite its relatively well-understood role as a reproductive and pro-social peptide, oxytocin
(OT) tells a more convoluted story in terms of its modulation of fear and anxiety. This …

Peptidergic and functional delineation of the Edinger-Westphal nucleus

MF Priest, SN Freda, IJ Rieth, D Badong… - Cell reports, 2023 - cell.com
Many neuronal populations that release fast-acting excitatory and inhibitory
neurotransmitters in the brain also contain slower-acting neuropeptides. These facultative …

[HTML][HTML] Edinger-Westphal peptidergic neurons enable maternal preparatory nesting

T Topilko, SL Diaz, CM Pacheco, F Verny… - Neuron, 2022 - cell.com
Optimizing reproductive fitness in mammalians requires behavioral adaptations during
pregnancy. Maternal preparatory nesting is an essential behavior for the survival of the …

Central afferents to the nucleus of the solitary tract in rats and mice

S Gasparini, JM Howland, AJ Thatcher… - Journal of …, 2020 - Wiley Online Library
The nucleus of the solitary tract (NTS) regulates life‐sustaining functions ranging from
appetite and digestion to heart rate and breathing. It is also the brain's primary sensory …

Green synthesis of controlled shape silver nanostructures and their peroxidase, catalytic degradation, and antibacterial activity

A Shafiq, AR Deshmukh, K AbouAitah… - Journal of Functional …, 2023 - mdpi.com
Nanoparticles with unique shapes have garnered significant interest due to their enhanced
surface area-to-volume ratio, leading to improved potential compared to their spherical …

Peptidergic neurons of the Edinger–Westphal nucleus express TRPA1 ion channel that is downregulated both upon chronic variable mild stress in male mice and in …

V Kormos, A Kecskés, J Farkas, T Gaszner… - Journal of Psychiatry and …, 2022 - jpn.ca
Background: Transient receptor potential ankyrin 1 (TRPA1), a cation channel, is expressed
predominantly in primary sensory neurons, but its central distribution and role in mood …

Fluoxetine treatment supports predictive validity of the three hit model of depression in male PACAP heterozygous mice and underpins the impact of early life adversity …

T Gaszner, J Farkas, D Kun, B Ujvári, G Berta… - Frontiers in …, 2022 - frontiersin.org
According to the three hit concept of depression, interaction of genetic predisposition altered
epigenetic programming and environmental stress factors contribute to the disease. Earlier …

A Sleep‐Specific Midbrain Target for Sevoflurane Anesthesia

T Yi, N Wang, J Huang, Y Wang, S Ren, Y Hu… - Advanced …, 2023 - Wiley Online Library
Sevoflurane has been the most widely used inhaled anesthetics with a favorable recovery
profile; however, the precise mechanisms underlying its anesthetic action are still not …

Gray areas: Neuropeptide circuits linking the Edinger-Westphal and Dorsal Raphe nuclei in addiction

MB Pomrenze, LC Walker, WJ Giardino - Neuropharmacology, 2021 - Elsevier
The circuitry of addiction comprises several neural networks including the midbrain-an
expansive region critically involved in the control of motivated behaviors. Midbrain nuclei …